Article

The frailty syndrome: definition and natural history.

Department of Medicine, Johns Hopkins University School of Medicine, 2024 East Monument Street, Suite 2-700, Baltimore, MD 21205-1179, USA.
Clinics in Geriatric Medicine (Impact Factor: 3.19). 02/2011; 27(1):1-15. DOI: 10.1016/j.cger.2010.08.009
Source: PubMed

ABSTRACT This article reviews the current state of knowledge regarding the epidemiology of frailty by focusing on 6 specific areas: (1) clinical definitions of frailty, (2) evidence of frailty as a medical syndrome, (3) prevalence and incidence of frailty by age, gender, race, and ethnicity, (4) transitions between discrete frailty states, (5) natural history of manifestations of frailty criteria, and (6) behavior modifications as precursors to the development of clinical frailty.

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