Article

Comprehensive meta-analysis of the risk of suicide in eating disorders

Centro Medico Genneruxi, Via Costantinopoli 42, Cagliari, Italy.
Acta Psychiatrica Scandinavica (Impact Factor: 5.55). 11/2010; 124(1):6-17. DOI: 10.1111/j.1600-0447.2010.01641.x
Source: PubMed

ABSTRACT Past meta-analyses on suicide in eating disorders included few available studies.
PubMed/Medline search for papers including sample n ≥40 and follow-up ≥5 years: 40 studies on anorexia nervosa (AN), 16 studies on bulimia nervosa (BN), and three studies on binge eating disorder (BED) were included.
Of 16,342 patients with AN, 245 suicides occurred over a mean follow-up of 11.1 years (suicide rate=0.124 per 100 person-years). Standardized mortality ratio (SMR) was 31.0 (Poisson 95% CI=21.0-44.0); a clear decrease in suicide risk over time was observed in recent decades. Of 1768 patients with BN, four suicides occurred over a mean follow-up of 7.5 years (suicide rate=0.030 per 100 person-years): SMR was 7.5 (1.6-11.6). No suicide occurred among 246 patients with BED (mean follow-up=5.3 years).
AN and BN share many risk factors for suicide: the factors causing lower suicide rates per person-year in BN compared to AN should be investigated.

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    • "If we consider that early detection of ED is associated with better treatment outcomes (van Son, van Hoek van Furth, Donker, & Hoek, 2010), and a decrease in suicide rates (Preti et al., 2011), it is of great importance that scientific research and clinical training consider specific gender aspects in the assessment and treatment of ED and body dissatisfaction in men. "
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