Modeling Rett Syndrome with Stem Cells

Howard Hughes Medical Institute at Massachusetts General Hospital, Center for Regenerative Medicine and Cancer Center, Boston, MA 02114, USA.
Cell (Impact Factor: 33.12). 11/2010; 143(4):499-500. DOI: 10.1016/j.cell.2010.10.037
Source: PubMed

ABSTRACT The discovery that somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) raised the exciting possibility of modeling diseases with patient-specific cells. Marchetto et al. (2010) now use iPSC technology to generate, characterize, and treat an in vitro model for the autism spectrum disorder Rett syndrome.

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