CT imaging of acute pulmonary embolism.

Thomas Henzler, J Michael Barraza, John W Nance, Philip Costello, Radko Krissak, Christian Fink, U Joseph Schoepf

Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA.

Journal Article: Journal of cardiovascular computed tomography 10/2010; 5(1):3-11. DOI: 10.1016/j.jcct.2010.10.001

Abstract

CT pulmonary angiography (CTPA) has become the de facto clinical "gold standard" for the diagnosis of acute pulmonary embolism (PE) and has replaced catheter pulmonary angiography and ventilation-perfusion scintigraphy as the first-line imaging method. The factors underlying this algorithmic change are rooted in the high-sensitivity and specificity, cost-effectiveness, and 24-hour availability of CTPA. In addition, CTPA is superior to other imaging methods in its ability to diagnose and exclude, in a single examination, a variety of diseases that mimic the symptoms of PE. This article reviews the current role of CTPA in the diagnosis of acute PE as well as more recent developments, such as the use of CT parameters of right ventricular dysfunction for patient prognostication and the assessment of lung perfusion with CT.

Source: PubMed

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Keywords

acute PE
 
acute pulmonary embolism
 
algorithmic change
 
article reviews
 
catheter pulmonary angiography
 
cost-effectiveness
 
CT
 
CT parameters
 
CT pulmonary angiography
 
CTPA
 
de facto clinical
 
factors
 
first-line imaging method
 
high-sensitivity
 
lung perfusion
 
patient prognostication
 
single examination
 
specificity
 
ventilation-perfusion scintigraphy
 
ventricular dysfunction