Article

Tandem Facial Amphiphiles for Membrane Protein Stabilization

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
Journal of the American Chemical Society (Impact Factor: 11.44). 11/2010; 132(47):16750-2. DOI: 10.1021/ja1072959
Source: PubMed

ABSTRACT We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

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