Article

Bladder metastasis of malignant melanoma: a case report and review of literature.

Department of Urology, University of Mersin School of Medicine, 33079 Mersin, Turkey.
Medical Oncology (Impact Factor: 2.06). 11/2010; 28 Suppl 1:S667-9. DOI: 10.1007/s12032-010-9730-x
Source: PubMed

ABSTRACT Metastatic malignant melanoma of the bladder is extremely rare in clinical practice with less than 10 cases reported in the last 30 years in the English literature. We report a case of malignant melanoma metastasis into the bladder, and review of the pertinent literature. A 60-year-old woman with a history of malignant melanoma in the distal phalanx on the right middle finger, excised 8 years ago presented with gross hematuria and weight loss. She underwent cystoscopy and complete transurethral resection of the bladder tumor. Pathological examination showed metastatic malignant melanoma of the bladder mucosa. The patient eventually died 7 months after transurethral resection.

0 Bookmarks
 · 
120 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: We present a case of a 61-year-old female presenting with a bladder tumor that occurred 7 years after her previous diagnosis of Clark's level III mid-back melanoma. The bladder tumor was submitted to histopathology without accompanying clinical history, and an initial diagnosis of high-grade urothelial carcinoma was rendered based on epithelioid and sarcomatoid appearing pleomorphic histopathology. We present this case to highlight the diagnostic challenge presented by the rare occurrence of metastatic melanoma to the urinary bladder and the potential pitfall of this lesion being diagnosed as high-grade urothelial carcinoma in the presence of limited clinical history.
    International Journal of Surgical Pathology 06/2013; 22(4). DOI:10.1177/1066896913492199 · 0.96 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Transitional cell carcinoma comprises more than 95% of the primary bladder tumors and primary adenocarcinoma is found in 1% of cases. Secondary adenocarcinoma of urinary bladder is a rare entity, accounting for less than 2% of all bladder tumors andis mostly found in advanced stages with peritoneal dissemination.Metastasis to urinary bladder from gastric adenocarcinoma is extremely rare and is associated with grave prognosis. Here-in we report a case of 62-year-old Saudi woman who was treated for gastric adenocarcinoma of lesser curvaturefour years ago;presented with the complaints of gross painless hematuria and on work-up was found to have a thickening of dome and left lateral wall of the urinary bladder. A transurethral biopsy of the bladder wall revealed well differentiated tubular adenocarcinoma metastatic from gastric carcinoma. After palliative radiotherapy to bladder, she was started on systemic chemotherapy.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Parotid malignancy may occur as a primary neoplasm of the salivary tissue or as metastatic involvement of the parotid lymph nodes. Primary tumors of squamous cell carcinoma and malignant melanoma involving the skin of the head and neck have the potential to spread to lymph nodes of the parotid gland. Metastatic malignant melanoma to the back was exceptionally rare and no such reports have been noted in the literature. We reported an exceptional case of intraparotid lymph nodes metastasis of the right scalp junctional nevus with malignant transformation to malignant melanoma in a 48-year-old man. The patient presented with a mass in the parotid gland area, which was misdiagnosed as a primary parotid tumor and surgical removal was performed. Unfortunately, recurrence with newly developed metastatic lesions in the back and cervical lymph nodes occurred 1 year after initial surgical management. This case is presented highlighting the unusual features of metastatic junctional nevus with malignant transformation to malignant melanoma of intraparotid lymph nodes, cervical lymph nodes and the back, which should help us to reduce misdiagnosis and obtain the best results.