Real Anal Leiomyoma: a Case Report

Servicio de Cirugía General, Hospital Universitario Reina Sofía, Córdoba, Spain.
Journal of Gastrointestinal Cancer (Impact Factor: 0.38). 03/2011; 42(1):54-6. DOI: 10.1007/s12029-010-9219-z
Source: PubMed


Leiomyoma of the rectum and anal canal is an unusual benign mesenchymal neoplasm that originates from smooth muscle cells. We describe the clinical presentation, MRI findings, and surgical treatment of a rare case of perianal leiomyoma confirmed by immunohistochemistry. We also report a review of the world's literature on the subject.

1 Follower
107 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: Mesenchymal anal and perianal tumors are relatively uncommon. The majority are malignant. Benign mesenchymal anal tumors are rare. Some are common stromal neoplasms, but with the rare presentation as anal polyps. Other lesions are rare, but unique to the anal/perianal region. Common keratinous cysts might uncommonly present as anal polyps, while other rare cysts are unique to the anogenital region. A retrospective review study of 493 anal and perianal specimens conducted over seven years showed twenty cases (4.0%) of benign anal polypoid lesions. We excluded the usual fibroepithelial polyps, anal tags, papilla, hemorrhoids and warts. We found six cysts, three lipomas, two papillary hidradenomas, two melanocytic nevi, one hamartoma, one xanthogranuloma, one seborrheic keratosis, one hematoma, one fibrous histiocytoma, one granular cell tumor and one lymphangioma. The male to female ratio was 1.5:1. They were found in adults (mean age 37.8years) and in infants (mean age 2.4years). In general, they were smaller than 2cm. They were either asymptomatic or presented with anal pain, bleeding or lumps. Some were clinically confused with the more common non-neoplastic anal tags, hemorrhoids and fibroepithelial polyps/papilla. A variety of common and rare benign lesions might present as anal polyps with important surgical and pathologic challenges and implications.
    Pathology - Research and Practice 10/2012; 208(12). DOI:10.1016/j.prp.2012.09.004 · 1.40 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Nonepithelial and nonmelanocytic anal neoplasms are uncommon. The majority are mesenchymal tumors, most of which are malignant sarcomas, particularly leiomyosarcomas and gastrointestinal stromal tumors. Benign mesenchymal anal neoplasms are even rarer. The most common reported cases were anal leiomyomas, granular cell tumors, fibroadenomas, and xanthogranulomas. Benign fibrous histiocytomas (BFHs) or dermatofibromas are common mesenchymal cutaneous tumors that occur in different sites and at any age. Review of the literature did not show previous reports of BFH arising in the anal canal region. We report the first case of a solitary BFH, an unexpected occurrence of a common tumor type presenting as a polyp in an unusual site such as the anus. This rare occurrence can present diagnostic challenges for the surgeons and pathologists. Clinically, it can be confused with the usual anal tags, fibroepithelial polyps, or hemorrhoids. Benign fibrous histiocytoma is a neoplasm with a potential of local recurrence and, therefore, carries certain clinical implications for the patients' management and follow-up when compared with the common nonneoplastic causes of anal polyps such as the anal tags of anal fissures, hemorrhoids, or fibroepithelial papilla. Histologically, it should be differentiated from other histiocytic lesions. This can be resolved by the application of certain histologic features with the appropriate immunohistochemical markers taken within the correct clinical context.
    Annals of Diagnostic Pathology 10/2013; 17(5):464-465. DOI:10.1016/j.anndiagpath.2012.07.008 · 1.12 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: Alveolar soft part sarcoma (ASPS) is a rare diagnosis in the perianal region. Methods: we describe the clinical presentation, pathological findings and differential diagnosis of a rare case of perianal ASPS. We also describe the importance of the preoperative embolization of the hypervascularised masses to prevent surgical bleeding. Conclusions: clinical and pathological findings are essential for the diagnosis, specifically by immunochemistry and molecular techniques, as the demonstration of ASPL/TFE3 fusion transcript became indispensable in some cases. Preoperative embolization of the hypervascularised masses may prevent uncontrollable surgical bleeding.
    Central European Journal of Medicine 04/2014; 9(2). DOI:10.2478/s11536-012-0145-2 · 0.15 Impact Factor

Similar Publications