Article

Disseminated intravascular coagulation with intracranial haematoma in neonatal congenital syphilis.

Department of Radiodiagnosis and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.
Journal of Tropical Pediatrics (impact factor: 1.39). 10/2010; 57(4):315-8. DOI:10.1093/tropej/fmq088 pp.315-8
Source: PubMed

ABSTRACT Disseminated intravascular coagulation (DIC) although a well known complication in neonatal sepsis is extremely rare in congenital syphilis and there are scanty reports of this entity in the literature. Intracranial bleeding following DIC in neonatal congenital syphilis is even rarer, and has been reported only once earlier. We are reporting the second case of neonatal DIC with intracranial haematoma due to congenital syphilis in a newborn. Our patient also had clinical and biochemical evidence of hepatitis which predisposes to DIC. Extensive investigations and emergent use of imaging modalities including ultrasound and CT scan led to early diagnosis and treatment in our patient, who could therefore be salvaged from an otherwise life threatening disease.

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    Article: [Bell's palsy and facial pain associated with toxocara infection].
    Arian Bachtiar, Herbert Auer, Josef Finsterer
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    ABSTRACT: Objectives: Toxocarosis involving cranial nerves is extremely rare and almost exclusively concerns the optic nerve. Toxocarosis involving the seventh cranial nerve has not been reported. Case report: A 33y male developed left-sided Bell's palsy two days after left-sided otalgia 6y before. Despite extensive diagnostic work-up at that time the cause of Bell's palsy remained unknown. During the following years Bell's palsy slightly improved but retromandibular pain remained almost unchanged and he developed enlarged lymph nodes along the jugular veins, submandibularly, and in the trigonum caroticum. Re-evaluation 6y later revealed an increased titer of serum antibodies against Toxocara canis and a positive Westernblot for Toxocara canis ES-antigen. Despite absent eosinophilia in the serum, toxocarosis was diagnosed and a therapy with albendazole initiated, with benefit for retromandibular pain, but hardly for Bell's palsy or enlarged lymph nodes. CSF investigations after albendazole revealed a positive Westernblot for antibodies against toxocara but absent pleocytosis or eosinophilia, and negative PCR for Toxocara canis. Conclusions: Visceral larva migrans due to Toxocara canis may be associated with Bell's palsy, retromandibular pain, and lymphadenopathy. A causal relation between Bell's palsy and the helminthosis remains speculative. Adequate therapy years after onset of the infestation may be of limited benefit.
    Revista chilena de infectologia: organo oficial de la Sociedad Chilena de Infectologia 10/2012; 29(5):551-3. · 0.45 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

biochemical evidence
 
congenital syphilis
 
CT scan
 
DIC
 
Disseminated intravascular coagulation
 
emergent use
 
imaging modalities
 
Intracranial
 
intracranial haematoma
 
known complication
 
neonatal congenital syphilis
 
neonatal DIC
 
neonatal sepsis
 
predisposes
 
second case
 

Shabnam Bhandari Grover