Article

Incidence of influenza virus infection in early infancy: a prospective study in South Asia.

Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
The Pediatric Infectious Disease Journal (impact factor: 3.58). 02/2011; 30(2):170-3. DOI:10.1097/INF.0b013e3181f63c39 pp.170-3
Source: PubMed

ABSTRACT We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.

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Keywords

10 additional rapid test-proven influenza cases
 
31 serologically
 
6 months
 
Bangladesh
 
infant sera
 
influenza hemagglutination inhibition antibody titer increases
 
tropical South Asia