Chiesa A, Serretti A. Mindfulness based cognitive therapy for psychiatric disorders: a systematic review and meta-analysis. Psychiatry Res 187: 441-453

Institute of Psychiatry, University of Bologna, Bologna, Italy.
Psychiatry Research (Impact Factor: 2.47). 05/2011; 187(3):441-53. DOI: 10.1016/j.psychres.2010.08.011
Source: PubMed


Mindfulness- based Cognitive Therapy (MBCT) is a meditation program based on an integration of Cognitive behavioural therapy and Mindfulness-based stress reduction. The aim of the present work is to review and conduct a meta-analysis of the current findings about the efficacy of MBCT for psychiatric patients. A literature search was undertaken using five electronic databases and references of retrieved articles. Main findings included the following: 1) MBCT in adjunct to usual care was significantly better than usual care alone for reducing major depression (MD) relapses in patients with three or more prior depressive episodes (4 studies), 2) MBCT plus gradual discontinuation of maintenance ADs was associated to similar relapse rates at 1year as compared with continuation of maintenance antidepressants (1 study), 3) the augmentation of MBCT could be useful for reducing residual depressive symptoms in patients with MD (2 studies) and for reducing anxiety symptoms in patients with bipolar disorder in remission (1 study) and in patients with some anxiety disorders (2 studies). However, several methodological shortcomings including small sample sizes, non-randomized design of some studies and the absence of studies comparing MBCT to control groups designed to distinguish specific from non-specific effects of such practice underscore the necessity for further research.

152 Reads
  • Source
    • "The MBSR program has been combined with CBT in the development of mindfulnessbased cognitive therapy (MBCT). It was developed for the prevention of major depressive disorder relapse [7], however evidence to support its use in anxiety and active depression continues to emerge [8]. The programs typically consist of 8 weekly 2.5 hour group sessions involving various forms of meditation, group discussion, and other exercises; one day of meditation retreat and approximately one hour of daily home practice [9]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Background. Functional gastrointestinal disorders are highly prevalent and standard treatments are often unsatisfactory. Mindfulness-based therapy has shown benefit in conditions including chronic pain, mood, and somatization disorders. Objectives. To assess the quality and effectiveness reported in existing literature, we conducted a meta-analysis of mindfulness-based therapy in functional gastrointestinal disorders. Methods. Pubmed, EBSCO, and Cochrane databases were searched from inception to May 2014. Study inclusion criteria included randomized, controlled studies of adults using mindfulness-based therapy in the treatment of functional gastrointestinal disorders. Study quality was evaluated using the Cochrane risk of bias. Effect sizes were calculated and pooled to achieve a summary effect for the intervention on symptom severity and quality of life. Results. Of 119 records, eight articles, describing seven studies, met inclusion criteria. In six studies, significant improvements were achieved or maintained at the end of intervention or follow-up time points. The studies had an unclear or high risk of bias. Pooled effects were statistically significant for IBS severity (0.59, 95% CI 0.33 to 0.86) and quality of life (0.56, 95% CI 0.47 to 0.79). Conclusion. Studies suggest that mindfulness based interventions may provide benefit in functional gastrointestinal disorders; however, substantial improvements in methodological quality and reporting are needed.
    Evidence-based Complementary and Alternative Medicine 09/2014; 2014. DOI:10.1155/2014/140724 · 1.88 Impact Factor
  • Source
    • "As observed from the results, mindfulness-based cognitive therapy is a useful method for decreasing the depression symptoms of male drug-dependent individuals. This finding is congruent with those of previous studies that also reported the effectiveness of MBCT on depression (Britton, Shahar, Szepsenwol, & Jacobs, 2012; Chiesa & Serretti, 2011; Kuyken et al., 2010). In Iran, Kaviani, Javaheri, and Bahirayi (2005) conducted a follow-up study 60 days after MBCT. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The present study aimed at examining the effect of Mindfulness-Based Cognitive Therapy (MBCT) in decreasing depression symptoms in dully diagnosed males (drug dependent males with co-morbid depression).An experimental research design with pre-and post-tests and a control group was used. The sample of the study comprised 33 drug-dependent men who also endorsed depression symptoms on the Beck Depression Inventory II (BDI-II). All the selected individuals were assigned randomly to either the intervention group or control group (16 to the intervention and 17 to the control group). The intervention group experienced eight 2-hour sessions of training in MBCT. At the end of the training, the subjects were once again evaluated using the BDI-II. Analysis of co-variance was used to analyze the data. The results suggested that MBCT did contribute to a significant decrease in the depression symptoms of the dully diagnosed individuals. It is recommended that the MBCT be used for treating depression in drug-dependent males undergoing detoxification and treatment for their drug dependence.
    Archives of psychiatric nursing 05/2014; 28(5). DOI:10.1016/j.apnu.2014.05.003 · 0.85 Impact Factor
  • Source
    • "Taken together, these findings suggest that individuals who are significantly distressed by relational aggression may engage in strategies to cope with the aggression though avoidance which despite the perceived reduction in distress, may actually increase their risk for future victimization and poor psychosocial outcomes. These findings are consistent with recent theories linking attempts to avoid internal experiences with a broad array of psychological problems (e.g., Bieling et al., 2012; Chiesa & Serretti, 2011; Hayes Hayes, Wilson, Gifford, Follette, & Strosahl, 1996), as well as experimental research demonstrating the paradoxically negative effects of suppression of thoughts (e.g., Abramowitz, Tolin, & Street, 2001) and emotions (e.g., Gross & Levenson, 1997). This suggests a program aimed at teaching individuals to understand their emotional responses to relational aggression, targeting the automatic and habitual use of experiential avoidance, and encouraging active problem-solving might be effective in reducing the negative outcomes of relational aggression. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Psychosocial consequences of relational aggression have garnered significant attention. Although most adolescents are targets of relational aggression at some point, only a sub-group experience significant psychological distress and impaired functioning, with research linking experiential avoidance to negative outcomes. The present study sought to develop and pilot a school-based risk-reduction program informed by acceptance-based behavioral theory aimed to reduce experiential avoidance and increase acceptance- and action-based coping to reduce psychosocial distress. Eight 7th grade classrooms comprising of 210 participants with a mean age of 12.45, were group-randomized to either immediate or waitlist condition. Multiple regressions conducted on baseline and three-month follow-up measures of peer victimization, peer aggression, experiential avoidance, psychopathology, and coping style. Baseline experiential avoidance was significantly associated both the extent to which a student engaged in, and was the victim of, both relational and physical aggression. The program group engaged in more problem-solving coping compared to the waitlist group at follow-up. Change in experiential avoidance predicted negative outcomes at follow-up across domains regardless of group assignment. Implications and recommendations for future studies are discussed.
    Journal of Contextual Behavioral Science 04/2014; 3(2). DOI:10.1016/j.jcbs.2014.03.001
Show more


152 Reads
Available from