Metastatic Pancreatic Small-Cell Carcinoma Presenting As Acute Pancreatitis

University of Wisconsin Hospital and Clinics, Madison, WI, USA.
Journal of Clinical Oncology (Impact Factor: 18.43). 12/2010; 28(36):e748-9. DOI: 10.1200/JCO.2010.30.4600
Source: PubMed
Download full-text


Available from: Christina Fitzmaurice, Feb 06, 2015
  • Source
    • "Each paper was inspected and the reference lists of the selected articles were also screened systematically for additional studies of interest. More than 20 cases of primary small cell carcinoma of the pancreas were excluded.1–6 Additionally, some cases with small cell cancer in the studies were analysed just to some extent because they did not describe the detailed clinical findings 7–18 Information regarding patient presentation, site of primary neoplasia, characteristics of metastasis in the pancreas, treatment, and patient demographics were summarised using descriptive statistics. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Few data are available concerning incidence, clinical picture, and prognosis for pancreatic metastases of small cell lung carcinoma. In this paper we review the related literature available in English language. Although pancreatic metastases are generally asymptomatic, they can rarely produce clinical symptoms or functional abnormalities. The widespread use of multi-detector computerised tomography (CT) in contemporary medical practice has led to an increased detection of pancreatic metastases in oncology patients. Tissue diagnosis is imperative because radiological techniques alone are incapable of differentiating them from primary pancreatic tumours. Pancreatic metastases occur in the relative end stage of small cell lung cancer. The main complications of these lesions, although rare, are acute pancreatitis and obstructive jaundice. Early chemotherapy can provide a survival benefit even in patients with mild acute pancreatitis or extrahepatic biliary obstruction.
    Radiology and Oncology 03/2014; 48(1):11-19. DOI:10.2478/raon-2013-0022 · 1.91 Impact Factor
    • "It was presented one case of a pancreatic small-cell carcinoma presenting as acute pancreatitis[7]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Pancreatic cancer is still considered to be one of the leading causes of cancer deaths. The most common of all the different types of pancreatic cancer is ductal original malignant tumors, and their clinical features are commonly characterized. However, for the rare tumors in the pancreatic region, the clinical features often vary, and detection of the cancers are detected late. Limited data are available to guide the management of very rare neoplasms of the pancreas. Therefore, to recognize or detect the rare tumors in the pancreatic region are of importance for the clinical practice.
    North American Journal of Medical Sciences 05/2011; 3(5):212-6. DOI:10.4297/najms.2011.3212
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Small cell carcinoma (SCC) of lung is a highly malignant tumour and is notorious for early and widespread metastasis at the time of presentation. However, metastasis to pancreas occurs uncommonly. Metastatic lesions comprise of 3% of all pancreatic malignancies. We hereby present a rare case report where patient presented with symptoms of acute pancreatitis & diagnosed with SCC of lung, retrospectively. This case emphasize that acute pancreatitis can be a manifestation of malignancy and fine needle aspiration cytology can play a diagnostic role in such cases.
    Journal of Clinical and Diagnostic Research 05/2015; 9(5):E13-E14. DOI:10.7860/JCDR/2015/12685.5980 · 0.23 Impact Factor