Radiological-pathological correlation of pleomorphic liposarcoma of the anterior mediastinum in a 17-year-old girl

University of California, Santa Cruz, 70 Pinto Lane, Novato, CA 94947, USA.
Pediatric Radiology (Impact Factor: 1.65). 12/2010; 40 Suppl 1(S1):S68-70. DOI: 10.1007/s00247-010-1797-1
Source: PubMed

ABSTRACT Liposarcoma is a soft-tissue sarcoma typically seen in adults. It is extremely rare in children. It most often occurs in the extremities or in the retroperitoneum. We present a very rare case of an anterior mediastinal liposarcoma of the pleomorphic subtype in a 17-year-old girl, along with radiological and pathological correlation. The location, patient age and histological subtype are exceedingly uncommon for this tumor.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Fetal MR imaging is very challenging due to the movement of fetus and the breathing motion of the mother. Current clinical protocols involve quick 2D scouting scans to determine scan plane and often several attempts to reorient the scan plane when the fetus moves. This makes acquisition of fetal MR images clinically challenging and results in long scan times in order to obtain images that are of diagnostic quality. Compared to 2D imaging, 3D imaging of the fetus has many advantages such as higher SNR and ability to reformat images in multiple planes. However, it is more sensitive to motion and challenging for fetal imaging due to irregular fetal motion in addition to maternal breathing and cardiac motion. This aim of this study is to develop a fast 3D fetal imaging technique to resolve the challenge of imaging the moving fetus. This 3D imaging sequence has multi-echo radial sampling in-plane and conventional Cartesian encoding through plane, which provides motion robustness and high data acquisition efficiency. The utilization of a golden-ratio based projection profile allows flexible time-resolved image reconstruction with arbitrary temporal resolution at arbitrary time points as well as high signal-to-noise and contrast-to-noise ratio. The nice features of the developed image technique allow the 3D visualization of the movements occurring throughout the scan. In this study, we applied this technique to three human subjects for fetal MRI and achieved promising preliminary results of fetal brain, heart and lung imaging.
    04/2014; 4(2):123-8. DOI:10.3978/j.issn.2223-4292.2014.04.08
  • [Show abstract] [Hide abstract]
    ABSTRACT: Single-twin demise can pose substantial risks for the surviving co-twin, including increased risk of fetal loss, preterm delivery, neurovascular injury, and end-organ damage. In this chapter, we summarise recently published research on the causes of single twin demise, the pathophysiology of injury to the surviving co-twin, and the evidence for current management strategies. The gestation at which single intrauterine fetal demise occurs, and the chorionicity of the multiple pregnancies, are the two most important factors when considering the risks to the surviving twin. Management should include fortnightly ultrasound scans for growth, umbilical artery Doppler studies, and liquor volume. In monochorionic twins, more complex Doppler assessment with middle cerebral artery Doppler velocimetry and a magnetic resonance imaging of the survivor's brain at least 3 weeks after single intrauterine fetal demise occurs should be carried out to look for evidence of neurological morbidity. With no other obstetric complications, dichorionic pregnancies can be delivered at term. Monochorionic pregnancies are more difficult to manage, and are often delivered between 34 and 36 weeks.
    Best practice & research. Clinical obstetrics & gynaecology 12/2013; DOI:10.1016/j.bpobgyn.2013.11.003 · 3.00 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Mediastinal lipomatous tumors with additional malignant soft tissue components are exceedingly rare. Patients can have substantially large sized tumors with long duration of symptoms and can be misinterpreted on radiographs. Enhancing soft tissue component within a fat density lesion within the mediastinum is alarming and should raise the suspicion of sarcomatous component. Along with diagnostic imaging, selective CT guided biopsy/FNAC from the enhancing soft tissue component can help in making correct diagnosis.
    Open Journal of Radiology 02/2014; 4(4):97-100. DOI:10.4236/ojrad.2014.41012

Full-text (2 Sources)

Available from
May 27, 2014