Radiological-pathological correlation of pleomorphic liposarcoma of the anterior mediastinum in a 17-year-old girl

University of California, Santa Cruz, 70 Pinto Lane, Novato, CA 94947, USA.
Pediatric Radiology (Impact Factor: 1.65). 12/2010; 40 Suppl 1(S1):S68-70. DOI: 10.1007/s00247-010-1797-1
Source: PubMed

ABSTRACT Liposarcoma is a soft-tissue sarcoma typically seen in adults. It is extremely rare in children. It most often occurs in the extremities or in the retroperitoneum. We present a very rare case of an anterior mediastinal liposarcoma of the pleomorphic subtype in a 17-year-old girl, along with radiological and pathological correlation. The location, patient age and histological subtype are exceedingly uncommon for this tumor.

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    ABSTRACT: Mediastinal lipomatous tumors with additional malignant soft tissue components are exceedingly rare. Patients can have substantially large sized tumors with long duration of symptoms and can be misinterpreted on radiographs. Enhancing soft tissue component within a fat density lesion within the mediastinum is alarming and should raise the suspicion of sarcomatous component. Along with diagnostic imaging, selective CT guided biopsy/FNAC from the enhancing soft tissue component can help in making correct diagnosis.
    Open Journal of Radiology 02/2014; 4(4):97-100. DOI:10.4236/ojrad.2014.41012

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