Imaging dynamic cellular events with quantum dots The bright future

Emory University and Georgia Institute of Technology.
Biochemist 06/2010; 32(3):12.
Source: PubMed


Semiconductor quantum dots (QDs) are tiny light-emitting particles that have emerged as a new class of fluorescent labels for biology and medicine. Compared with traditional fluorescent probes, QDs have unique optical and electronic properties such as size-tuneable light emission, narrow and symmetric emission spectra, and broad absorption spectra that enable the simultaneous excitation of multiple fluorescence colours.

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Available from: Shuming Nie, Feb 17, 2014
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    • "These QDs were susceptible to effective receptor-mediated endocytosis in cultured HeLa cells. Since these first demonstrations of QDs potential, their unique properties have been continuously optimized and applied in a plethora of bioapplications, ranging from fluorescent probes, biosensors to therapeutics and theranostic agents (Akerman et al., 2002; Smith et al., 2006; Li et al., 2009; Liu et al., 2010; Ruan et al., 2012; Singh et al., 2012). Once QDs that show paramount optical properties are those synthesized in organic media, numerous methods have been developed for creating hydrophilic QDs (Medintz et al., 2008). "
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