Article

A new look at the big five factor structure through exploratory structural equation modeling.

Department of Education, University of Oxford, Oxford, England.
Psychological Assessment (impact factor: 2.99). 09/2010; 22(3):471-91. DOI:10.1037/a0019227 pp.471-91
Source: PubMed

ABSTRACT NEO instruments are widely used to assess Big Five personality factors, but confirmatory factor analyses (CFAs) conducted at the item level do not support their a priori structure due, in part, to the overly restrictive CFA assumptions. We demonstrate that exploratory structural equation modeling (ESEM), an integration of CFA and exploratory factor analysis (EFA), overcomes these problems with responses (N = 3,390) to the 60-item NEO-Five-Factor Inventory: (a) ESEM fits the data better and results in substantially more differentiated (less correlated) factors than does CFA; (b) tests of gender invariance with the 13-model ESEM taxonomy of full measurement invariance of factor loadings, factor variances-covariances, item uniquenesses, correlated uniquenesses, item intercepts, differential item functioning, and latent means show that women score higher on all NEO Big Five factors; (c) longitudinal analyses support measurement invariance over time and the maturity principle (decreases in Neuroticism and increases in Agreeableness, Openness, and Conscientiousness). Using ESEM, we addressed substantively important questions with broad applicability to personality research that could not be appropriately addressed with the traditional approaches of either EFA or CFA.

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    Article: Cytokine production by leukocytes of military personnel with depressive symptoms after deployment to a combat-zone: a prospective, longitudinal study.
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    ABSTRACT: Major depressive disorder (MDD) is frequently diagnosed in military personnel returning from deployment. Literature suggests that MDD is associated with a pro-inflammatory state. To the best of our knowledge, no prospective, longitudinal studies on the association between development of depressive symptomatology and cytokine production by peripheral blood leukocytes have been published. The aim of this study was to investigate whether the presence of depressive symptomatology six months after military deployment is associated with the capacity to produce cytokines, as assessed before and after deployment. 1023 military personnel were included before deployment. Depressive symptoms and LPS- and T-cell mitogen-induced production of 16 cytokines and chemokines in whole blood cultures were measured before (T0), 1 (T1), and 6 (T2) months after return from deployment. Exploratory structural equation modeling (ESEM) was used for data reduction into cytokine patterns. Multiple group latent growth modeling was used to investigate differences in the longitudinal course of cytokine production between individuals with (n = 68) and without (n = 665) depressive symptoms at T2. Individuals with depressive symptoms after deployment showed higher T-cell cytokine production before deployment. Moreover, pre-deployment T-cell cytokine production significantly predicted the presence of depressive symptomatology 6 months after return. There was an increase in T-cell cytokine production over time, but this increase was significantly smaller in individuals developing depressive symptoms. T-cell chemokine and LPS-induced innate cytokine production decreased over time and were not associated with depressive symptoms. These results indicate that increased T-cell mitogen-induced cytokine production before deployment may be a vulnerability factor for development of depressive symptomatology in response to deployment to a combat-zone. In addition, deployment to a combat-zone affects the capacity of T-cells and monocytes to produce cytokines and chemokines until at least 6 months after return.
    PLoS ONE 01/2011; 6(12):e29142. · 4.09 Impact Factor

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Keywords

13-model ESEM taxonomy
 
60-item NEO-Five-Factor Inventory
 
broad applicability
 
CFA
 
CFAs
 
confirmatory factor analyses
 
correlated uniquenesses
 
decreases
 
differentiated
 
exploratory factor analysis
 
exploratory structural equation modeling
 
gender invariance
 
item level
 
item uniquenesses
 
latent
 
NEO instruments
 
overly restrictive CFA assumptions
 
priori structure due
 
substantively
 
traditional approaches