Association between Diabetes Mellitus and Oral Health Status in Japanese Adults

Department of Oral Health Promotion, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
International Journal of Oral Science (Impact Factor: 2.53). 06/2010; 2(2):82-9. DOI: 10.4248/IJOS10025
Source: PubMed


The objective of this study was to analyze the oral health among Japanese adults, with and without diabetes mellitus.
The subjects were 518 community residents aged 20 to 91 years in Japan, who participated in the "Akita health and nutrition survey" and the "Akita dental disease survey", conducted in 2006. The surveys comprised a self-administered questionnaire, along with medical and dental examinations.
Using the community periodontal index (CPI), the mean numbers of sextants presenting codes 0, 1 and 2 were significantly lower in diabetics than non-diabetics among the 59 years or younger age group. Although the mean numbers of sextants with codes 0, 1 and 2 among the 60 to 69 years age group were lower, and sextants with a code X among the 59 years or younger age group were higher in diabetics than non-diabetics, no statistically significant differences were detected. The tendency of lower mean numbers of natural teeth and functional tooth units in diabetics than non-diabetics was observed, however no differences were statistically significant.
The outcome of periodontal disease seemed to be influenced by the diabetic state to some degree, but a clear association between diabetes and oral health status was not found.

17 Reads
  • Source
    • "7 patients were smokers. 9 patients suffered from systemic diseases for which an association with periodontitis is reported or speculated in the medical literature, as follows: 1 essential hypertension (Tsioufis et al. 2011; Vidal et al. 2011), 1 hearth vessels alterations (Armitage 2000; Ford et al. 2010), 1 Parkinson (Hanaoka and Kashihara 2009; Persson et al. 1992; Schwarz et al. 2006), 1 chronic bronchitis (Brondum 1992; Garcia et al. 2001), 1 diabetes type II (Choi et al. 2011; Santos et al. 2010; Ueno et al. 2010), 1 osteoporosis (Megson et al. 2010; Persson et al. 2011; Renvert et al. 2011; Sultan and Rao 2011). Although the strong interest in the medical literature for the relationship between these diseases and periodontal diseases , until now there are insufficient evidence to establish direct causal relationship and the biological mechanisms of the association. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The diagnoses of periodontal diseases (PD) are primarily based on clinical examination and radiographic parameters. In this pilot exploration we want to supply some evidence whether metabonomic profiling of saliva samples can provide a signature of the disease. Saliva samples were analyzed by Nuclear Magnetic Resonance (NMR) metabonomics from 22 healthy subjects (HS) and 32 patients with clinic and radiographic diagnosis of dif-ferent PD: Gingivitis (G), Localized Chronic Periodontitis (LCP), Generalized Chronic Periodontitis (GCP), Local-ized Aggressive Periodontitis (LAP), and Generalized Aggressive Periodontitis (GAP). Pattern recognition anal-ysis of NMR profiles can discriminate GCP patients (n = 21) from HS (n = 22) with an accuracy of 84.1%. Metabolic profiles of GCP patients exhibited higher con-centrations of acetate, c-aminobutyrate, n-butyrate, succi-nate, trimethylamine, propionate, phenylalanine and valine, and decreased concentrations of pyruvate and N-acetyl groups compared with controls. Our results can provide a contribution to the understanding of the biochemical net-work and pathway in the GCP and other PD, however at this stage the method can not be extended to the general population as a ready-to-use clinical tool, due to the limited cohort recruited and the exploratory nature of this work. Anyway, a further validation of the statistical model on a larger cohort is in progress with the aim to demonstrate the potential impact in clinical practice of our findings.
    Metabolomics 06/2012; DOI:10.1007/s11306-011-0331-2 · 3.86 Impact Factor
  • Source
    • "CHD subjects with diabetes and smoking having missing teeth were five times higher in number and two times higher with a mean tooth loss than the healthy subjects. These results support the previous studies [22] [23] showing that smoking and diabetes significantly contribute to tooth loss. However, cardiac patients of this study remained 1.232 times at higher risk for tooth loss, and this association was observed independent of confounding factors. "
    [Show abstract] [Hide abstract]
    ABSTRACT: To observe frequency and possible association of tooth loss with prevalent coronary heart disease in Pakistani population. Angiographically determined coronary heart disease (CHD) patients of Punjab Institute of Cardiology, Lahore, Pakistan, and healthy individuals were enrolled for status of tooth loss. Nine hundred and thirty six CHD patients and 595 healthy subjects with mean age of 51.9±8.4years were examined. Mean (±SD) tooth loss was significantly (P⩽0.001) higher in cardiac patients (9.8±9.2) than healthy subjects (6.8±6.9) with odds ratio (OR)=1.543 (95%CI=1.985-2.851). Tooth loss was significantly (P⩽0.001) associated with CHD males and females and cardiac patients with diabetes and smoking. After adjustment of age, gender, diabetes and smoking, subjects with CHD were more likely to have higher tooth loss. Tooth loss was significantly associated with prevalent CHD independent of classic risk factors of age, gender, smoking and diabetes in this study sample.
    03/2012; 2(1):51-6. DOI:10.1016/j.jegh.2011.11.004
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Aims We conducted an intervention study to clarify how effectively a telemedicine system using a multi-functional videophone could be used in lifestyle guidance, with special focus on diet for diabetic patients cared for at home. Methods Patients were assigned to a 3-month intervention group or to a usual care group. In the intervention group, patients and a medical professional communicated bi-directionally through a videophone-based communication system for 30 min, once a week. The participants were encouraged to send pictures of each meal online, through the videophone system, in real time. Results In intra-subjective comparison, the 3-month intervention program resulted in a significant decrease in body weight (BW) (p < 0.0005) and average HbA1C level (p < 0.005) compared with before the intervention program. Three months after the conclusion of the intervention program, average HbA1C levels returned to almost the same levels as before intervention (p < 0.05). In the usual care group, average HbA1C level did not change significantly for 6 months. Conclusions 3-month intensive communication using the multimodal videophone system led to a significant decrease in BW and average HbA1C level. This novel bi-directional communication is useful for improving conditions such as diabetes, BW, and hyperglycemia for homecare diabetes patients, thus, reducing cardiovascular risk.
    Diabetology International 03/2012; 4(1). DOI:10.1007/s13340-012-0096-5
Show more


17 Reads
Available from