The first national public breast cancer screening program in Saudi Arabia
ABSTRACT Despite its relatively low incidence in Saudi Arabia, breast cancer has been the most common cancer among Saudi females for the past 12 consecutive years. The objective of this study was to report the results of the first national public breast cancer screening program in Saudi Arabia.
Women 40 years of age or older underwent breast cancer screening. Mammograms were scored using the Breast Imaging-Reporting and Data System (BI-RADS). Correlations between imaging findings, risk factors and pathological findings were analyzed.
Between September 2007 and April 2008, 1215 women were enrolled. The median age was 45 years, and median body mass index was 31.6 kg/m 2 . Sixteen cases of cancer were diagnosed. No cancer was diagnosed in 942 women with R1/R2 scores, and only 1 case of cancer was diagnosed in 228 women with R0/R3 scores. However, among 26 women with R4/R5 scores, 50% had malignant disease and 35% had benign lesions. No correlation was found between known risk factors and imaging score or cancer diagnosis.
Public acceptance of the breast cancer screening program was encouraging. Longitudinal follow-up will help in better determining the risk factors relevant to our patient population.
Article: Patient Perspective.The Oncologist 01/2014; DOI:10.1634/theoncologist.2013-0332 · 4.54 Impact Factor
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ABSTRACT: To identify the diagnostic role of total and free prostate-specific antigen (TPSA and FPSA) in breast cancer in women. Blood samples of 55 women with breast cancer were prospectively analyzed for PSA before and after breast surgery, with a control group of 82 healthy women. Total and free PSA levels were significantly higher in women with breast cancer (preoperatively) than in healthy women (P<0.001). Both serum TPSA and FPSA showed a significant decline in their pre-surgical values after surgical removal of the tumor (P<0.001). A significant proportion of breast cancer patients (83.6%) had free PSA as the predominant molecular form in serum as compared to 0% of controls and 1.8% of postoperative groups (P<0.001). TPSA and FPSA levels were significantly associated with younger age and earlier cancer stage, whereas no significant association was found between these two variables and FPSA as a predominant molecular form. This study indicated a clinical significance of preoperative measurement of serum TPSA and FPSA in the diagnosis of women with breast cancer, and may be a useful marker for monitoring the response to treatment.08/2013; DOI:10.1016/j.canep.2013.06.009
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ABSTRACT: To elicit knowledge of breast cancer, perception of occurrence, and behavior in relation to breast self-examination (BSE). A cross-sectional survey was carried out at the Department of Pathology, Medical College, University of Hail, Hail, Kingdom of Saudi Arabia for local occupants from Hail city and its rural neighborhood between September 2010 and February 2012. A personal interview-administered descriptive questionnaire and both descriptive and inferential statistics were used. A total of 1000 participants agreed to be involved, out of which 87.7% were females, 7.2% were males and 5.1% had undisclosed gender. The age range for participants was 12-66 years. Out of all participants, 44% did not know that breast cancer is an abnormal growth and 78% failed to recognise its multi-factorial nature, with Increased age being the least recognised single risk factor 4.8%. Scores showed that 61.5% had a low level of breast cancer related knowledge. Out of the participants who knew of someone who had breast cancer 73%, 50.1% said the disease was discovered at a Late stage mainly by Chance. Data for BSE indicated that 50.1% of female participants >16 years old did not practice BSE, and Fear was the main declared perceived reason. This study demonstrates a low level of fundamental knowledge of breast cancer and fear to practice BSE.Saudi medical journal 07/2013; 34(7):681-8. · 0.55 Impact Factor