Nevus lipomatosus cutaneous superficialis (NLCS) is an uncommon benign hamartomatous condition characterized by the presence of mature ectopic adiopocytes in the dermis. Clinically they are classified into two forms. The classical form is characterized by groups of multiple, non-tender, soft, pedunculated, cerebriform, yellowish or skin-colored papules, nodules, or plaques. The other form of NLCS clinically manifests as a solitary dome-shaped or sessile papule. The classical NLCS is mostly reported to involve the pelvic or gluteal region. We report here a case of adult-onset classical NLCS on the pinna because of its rarity and unusual location. In addition, our patient also had some rare features of NLCS, such as onset in the latter part of life, presence of foul-smelling discharge, and comedo-like plugs on the lesions.
"In two previously reported cases, surface of nevus was studded with multiple open comedons,2,17 and foul-smelling discharge may be associated.2 NLCS has been reported in association with other cutaneous disorders; follicular papules and hypertrophic pilo-sebaceous units,18 angiokeratoma of Fordyce,4 scattered leukoderma, café-au-lait macules,2 and hemangioma.4 In our study, no associated skin abnormalities were present. "
[Show abstract][Hide abstract] ABSTRACT: Introduction
Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign hamartomatous skin tumor characterized by dermal deposition of mature adipose tissue. It’s classified in two types: the classical form with multiple soft, pedunculated, cerebriform papules and nodules that coalesce into plaques, and the solitary form that consists of a solitary papule or nodule. In this study, eight cases of NLCS are reported.
The study was a retrospective case series including all patients with histopathologically documented NLCS who attended the Dermatology Department of Charles Nicolle hospital between January 1997 and December 2010. The objective of our study was to determine the epidemioclinical characteristics, the histopathologic features, and the treatment of this hamartoma. Patients included three males and five females aged between 7 and 41 years.
In four cases hamartoma was present since childhood, and in the other four cases it appeared in the third and fourth decades. Classical form was noted in seven cases and the solitary form in one case. Lesions involved limbs in four patients and trunk in four patients. Seven patients underwent surgical excision, and for one case no treatment was proposed.
The multiple or classical form is largely predominant in our study. Habitually, NLCS has an asymptomatic course. Treatment is usually not necessary unless for cosmetic reasons; surgical excision is curative and recurrence after is rare.
Dermatology and Therapy 12/2011; 1(2):25-30. DOI:10.1007/s13555-011-0006-y
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