Going tubular in the rostral migratory stream: neurons remodel astrocyte tubes to promote directional migration in the adult brain.

Neuroscience Center and the Department of Cell and Molecular Physiology, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Neuron (Impact Factor: 15.98). 07/2010; 67(2):173-5. DOI: 10.1016/j.neuron.2010.07.013
Source: PubMed

ABSTRACT Newly generated neuroblasts from the subventricular zone of the adult brain migrate as neuronal chains within a network of astroglial tubes in the rostral migratory stream. This highly directed, rapid migration channels new neurons to the olfactory bulb. In this issue of Neuron, Kaneko et al. demonstrate that migrating neurons dynamically remodel the morphology and organization of astroglial tubes to promote long distance, directional migration of neurons in the adult brain.

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