Publication of population data of linearly inherited DNA markers in the International Journal of Legal Medicine
ABSTRACT This manuscript extends on earlier recommendations of the editor of the International Journal of Legal Medicine on short tandem repeat population data and provides details on specific criteria relevant for the analysis and publication of population studies on haploid DNA markers, i.e. Y-chromosomal polymorphisms and mitochondrial DNA. The proposed concept is based on review experience with the two forensic haploid markers databases YHRD and EMPOP, which are both endorsed by the International Society for Forensic Genetics. The intention is to provide guidance with the preparation of population studies and their results to improve the reviewing process and the quality of published data. We also suggest a minimal set of required information to be presented in the publication to increase understanding and use of the data. The outlined procedure has in part been elaborated with the editors of the journal Forensic Science International Genetics.
Conference Paper: Congestion management under deregulated fuzzy environment[Show abstract] [Hide abstract]
ABSTRACT: In this paper, an efficient and practical hybrid model has been proposed for congestion management analysis for both real and reactive power transaction under deregulated fuzzy environment of power system. The proposed hybrid model determines the optimal bilateral or multilateral transaction and their corresponding load curtailment in two stages. In the first stage classical gradient descent optimal power flow algorithm has been used to determine the set of feasible curtailment strategies for different amount of real and reactive power transactions. Whereas in the second stage fuzzy decision opinion matrix has been used to select the optimal transaction strategy considering increase in private power transaction, reduction in percentage curtailment, and its corresponding change in per unit generation cost and hence profit as fuzzy variables. The performance of the proposed algorithm has been tested using modified IEEE 30 bus test system. The solutions so obtained are found to be quite encouraging and reliable refer to both utility and customers.Electric Utility Deregulation, Restructuring and Power Technologies, 2004. (DRPT 2004). Proceedings of the 2004 IEEE International Conference on; 05/2004
- Deutsche Zeitschrift für die Gesamte Gerichtliche Medizin 09/2010; 124(5):351. DOI:10.1007/s00414-010-0495-8 · 2.60 Impact Factor
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ABSTRACT: Complete mitochondrial control region data were generated for 230 unrelated Pathans from North West Frontier Province and Federally Administered Tribal Areas of Pakistan. To confirm data quality and to explore the genetic structure of Pathans, mitochondrial DNA haplogroup affiliation was determined by shared haplogroup-specific polymorphisms in the control region and by the analysis of diagnostic coding region single-nucleotide polymorphisms using a multiplex system for the assignment of eight haplogroups: M, N1'5, W, R, R0, T, J, and U. Sequence comparison revealed that 193 haplotypes were defined by 215 variable sites when major insertions were ignored at nucleotide positions 16193, 309, and 573. From a phylogenetic perspective, Pathans have a heterogeneous origin, displaying a high percentage of West Eurasian haplogroups followed by haplogroups native to South Asia and a small fraction from East Asian lineages. In population comparisons, this ethnic group differed significantly from several other ethnic groups from Pakistan and surrounding countries. These results suggest that frequency estimates for mtDNA haplotypes should be determined for endogamous ethnic groups individually instead of pooling data for these subpopulations into a single dataset for the Pakistani population. Data presented here may contribute to the accuracy of forensic mtDNA comparisons in the Pathans of Pakistan.Deutsche Zeitschrift für die Gesamte Gerichtliche Medizin 12/2010; 125(6):841-8. DOI:10.1007/s00414-010-0540-7 · 2.60 Impact Factor