Article

Cloud computing and the DNA data race.

Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA.
Nature Biotechnology (Impact Factor: 39.08). 07/2010; 28(7):691-3. DOI: 10.1038/nbt0710-691
Source: PubMed
2 Bookmarks
 · 
90 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: There is a widening gap between the throughput of massive parallel sequencing machines and the ability to analyze these sequencing data. Traditional assembly methods requiring long execution time and large amount of memory on a single workstation limit their use on these massive data.
    BMC Bioinformatics 01/2014; 15 Suppl 9:S2. · 2.67 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Plant genetic resources collection and utilization had made a huge impact in balancing the genetic diversity of the existing crop plant species and their application in genome based studies had also increased widely. Primarily studies were based on model species, although it now enhances the transferability of information to crops and related species. With the tremendous outbreak of new high-throughput technologies like next-generation sequencing (NGS) and reduction in their costs are bringing many more plants within the range of genome and transcriptome level analysis. The completion of reference genome sequences for many important crops and the ability to perform high-throughput resequencing are providing opportunities for improving our understanding of the crop plant genetic resources to accelerate crop improvement. The future of crop improvement will be centred on comparisons of individual crop plant genomes, and some of the best opportunities may lie in using combinations of new genetic mapping strategies and evolutionary analyses to direct and optimize the discovery and use of genetic variation. Here I review the importance of crop plant genetic resources and insights that have been emerged in recent years.
    Advances in Bioscience and Biotechnology 01/2012; 3(4):378-385.
  • Source

Full-text

Download
1 Download
Available from