Article

Design and Implementation of the Hispanic Community Health Study/Study of Latinos

Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Annals of epidemiology (Impact Factor: 2.15). 08/2010; 20(8):629-41. DOI: 10.1016/j.annepidem.2010.03.015
Source: PubMed

ABSTRACT The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a comprehensive multicenter community based cohort study of Hispanics/Latinos in the United States.
The Study rationale, objectives, design, and implementation are described in this report.
The HCHS/SOL will recruit 16,000 men and women who self-identify as Hispanic or Latino, 18 to 74 years of age, from a random sample of households in defined communities in the Bronx, Chicago, Miami, and San Diego. The sites were selected so that the overall sample would consist of at least 2000 persons in each of the following origin designations: Mexican, Puerto Rican and Dominican, Cuban, and Central and South American. The study includes research in the prevalence of and risk factors for heart, lung, blood and sleep disorders, kidney and liver function, diabetes, cognitive function, dental conditions, and hearing disorders.
The HCHS/SOL will (1) characterize the health status and disease burden in the largest minority population in the United States; (2) describe the positive and negative consequences of immigration and acculturation of Hispanics/Latinos to the mainstream United States life-styles, environment and health care opportunities; and (3) identify likely causal factors of many diseases in a population with diverse environmental exposures, genetic backgrounds, and early life experiences.

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    • "The baseline clinical examination (2008e2011) included comprehensive biological (e.g., anthropometrics, blood draw, oral glucose tolerance test, ankle brachial pressure index, electrocardiogram), behavioral (e.g. dietary intake assessed with two 24-h recalls, sleep habits, overnight sleep exam for apneic events) and socio-demographic (e.g., socioeconomic status, migration history) assessments (Lavange et al., 2010; Sorlie et al., 2010). HCHS/SOL selected households with a stratified 2-stage probability sampling design. "
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    ABSTRACT: Sleep is an important pillar of health and a modifiable risk factor for diabetes, stroke and obesity. Little is known of diet and sleep patterns of Hispanics/Latinos in the US. Here we examine eating behavior as a function of sleep duration in a sub-sample of 11,888 participants from the Hispanic Community Health Study/Study of Latinos, a community-based cohort study of Hispanics aged 18-74 years in four US cities. Using a cross-sectional probability sample with self-report data on habitual sleep duration and up to two 24-h dietary recalls, we quantified the Alternative Healthy Eating Index (AHEI-2010) score and intake of selected nutrients related to cardiovascular health. Linear regression models were fit to estimate least-square means of usual nutrient intake of saturated fats, potassium density, fiber, calcium, caffeine and the AHEI-2010 score, a measure of diet quality, by sleep duration adjusting for age, sex, Hispanic/Latino background, income, employment status, education, depressive symptomology, and years lived in the US. Distribution of calories over the day and association with sleep duration and BMI were also examined. Short sleepers (≤6 h) had significantly lower intake of potassium, fiber and calcium and long sleepers (≥9 h) had significantly lower intake of caffeine compared to others sleepers after adjusting for covariates. However no difference in the AHEI-2010 score was seen by sleep duration. Significantly more long sleepers, compared to intermediate and short sleepers, reported having ≥30% total daily calories before bedtime. Not consuming a snack or meal within 3 h before bedtime was associated with higher AHEI-2010 scores These findings identify novel differences in dietary patterns among short and long sleepers in a Hispanic/Latino population in the U.S. CLINICALTRIALS. NCT02060344. Copyright © 2015. Published by Elsevier Ltd.
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    • "Study variables and their instruments were selected to provide a comprehensive overview of the major determinants of cardiometabolic risk and included physiological, psychosocial, cultural, familial, and behavioral variables (Table 2). Complete characterization of parents' own risk profile is available from the HCHS/SOL baseline examination [22]. "
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    Annals of epidemiology 10/2013; 24(1). DOI:10.1016/j.annepidem.2013.08.008 · 2.15 Impact Factor
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    ABSTRACT: The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a multicenter, community-based cohort study of Hispanic/Latino adults in the United States. A diverse participant sample is required that is both representative of the target population and likely to remain engaged throughout follow-up. The choice of sample design, its rationale, and benefits and challenges of design decisions are described in this study. The study design calls for recruitment and follow-up of a cohort of 16,000 Hispanics/Latinos 18-74 years of age, with 62.5% (10,000) over 44 years of age and adequate subgroup sample sizes to support inference by Hispanic/Latino background. Participants are recruited in community areas surrounding four field centers in the Bronx, Chicago, Miami, and San Diego. A two-stage area probability sample of households is selected with stratification and oversampling incorporated at each stage to provide a broadly diverse sample, offer efficiencies in field operations, and ensure that the target age distribution is obtained. Embedding probability sampling within this traditional, multisite cohort study design enables competing research objectives to be met. However, the use of probability sampling requires developing solutions to some unique challenges in both sample selection and recruitment, as described here.
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