Article

Pneumococcal bacteremia in febrile infants presenting to the emergency department 8 years after the introduction of pneumococcal conjugate vaccine in the Basque Country of Spain.

Pediatric Emergency Department, Hospital de Cruces, Bizkaia, Spain.
The Pediatric Infectious Disease Journal (impact factor: 3.58). 12/2010; 29(12):1142-4. DOI:10.1097/INF.0b013e3181eaf89a pp.1142-4
Source: PubMed

ABSTRACT We included 3088 well-appearing infants aged between 3 and 36 months with fever without a source with a blood culture done as part of their study of fever. Rate of positive blood cultures for Streptococcus pneumoniae occult bacteremia (OB) was 0.58%. Rate of OB caused by PCV7-serotypes and nonvaccine serotypes were 0.16% and 0.42%, respectively. A total of 18 cases of S. pneumoniae OB were identified between January 1, 2006 and December 31, 2009. None of the 5 infants who had S. pneumoniae OB caused by vaccine serotypes had received PCV7. The decline in pneumococcal OB rates observed after PCV7 introduction in our area (Basque Country, Spain) continues 8 years later. There is no evidence of an OB rate increase caused by non-PCV7 serotypes.

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Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

3088 well-appearing infants
 
36 months
 
5 infants
 
8 years
 
Basque Country
 
blood culture
 
December 31
 
January 1
 
non-PCV7 serotypes
 
nonvaccine serotypes
 
OB
 
OB rate increase
 
pneumococcal OB rates
 
positive blood cultures
 
S. pneumoniae OB
 
vaccine serotypes
 

Javier Benito-Fernández