Sexual desire and the female sexual function index (FSFI): a sexual desire cutpoint for clinical interpretation of the FSFI in women with and without hypoactive sexual desire disorder.

New England Research Institutes, Inc., Watertown, MA 02472, USA.
Journal of Sexual Medicine (Impact Factor: 3.15). 09/2010; 7(9):3096-103. DOI: 10.1111/j.1743-6109.2010.01871.x
Source: PubMed

ABSTRACT A validated cutpoint for the total Female Sexual Function Index scale score exists to classify women with and without sexual dysfunction. However, there is no sexual desire (SD) domain-specific cutpoint for assessing the presence of diminished desire in women with or without a sexual desire problem.
This article defines and validates a specific cutpoint on the SD domain for differentiating women with and without hypoactive sexual desire disorder (HSDD).
Eight datasets (618 women) were included in the development dataset. Four independent datasets (892 women) were used in the validation portion of the study.
Diagnosis of HSDD was clinician-derived. Receiver-operator characteristic (ROC) curves were used to develop the cutpoint, which was confirmed in the validation dataset.
The use of a diagnostic cutpoint for classifying women with SD scores of 5 or less on the SD domain as having HSDD and those with SD scores of 6 or more as not having HSDD maximized diagnostic sensitivity and specificity. In the development sample, the sensitivity and specificity for predicting HSDD (with or without other conditions) were 75% and 84%, respectively, and the corresponding sensitivity and specificity in the validation sample were 92% and 89%, respectively.
These analyses support the diagnostic accuracy of the SD domain for use in future observational studies and clinical trials of HSDD.

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    ABSTRACT: Objectives: This study was performed to identify the relationship among sexual desire, other domains of sexual function and quality of life (QOL) and to describe the effect of sexual desire on sexual function and QOL in married women with hypoactive sexual desire disorder (HSDD). Methods: A total of 397 women with HSDD participated in this study. Data were collected through self-reported questionnaire which were constructed to include general characteristics items, Female Sexual Function Index (FSFI), and QOL tool. Data were analyzed using SPSS/WIN20 for descriptive statistics, t-test, one-way ANOVA, Duncan, partial correlation coefficients, and Hierarchial multiple regression. Results: There were significant correlations with sexual desire and other domains of sexual function. And also, sexual desire had a positive correlations with the psychological status and total QOL. The sexual desire was statistically significant predictors for sexual function and QOL. Conclusions: Health professionals should direct efforts toward developing sexual health-related counseling or education programs for women suffering from sexual dysfunction with the goal of helping them to achieve satisfying sex lives and improved quality of life.
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