Article

Direct visualization of cardiac radiofrequency ablation lesions.

School of Medicine, Stanford University, Stanford, CA, USA.
Journal of Cardiovascular Translational Research (impact factor: 2.61). 06/2009; 2(2):198-201. DOI:10.1007/s12265-009-9094-9 pp.198-201
Source: PubMed

ABSTRACT Effective ablation of atrial fibrillation and other cardiac arrhythmias requires precise catheter navigation and controlled delivery of energy to cardiac tissue. In this study, we summarize our initial experience using a fiber optic direct visualization catheter to evaluate and guide placement of endocardial radiofrequency (RF) ablation lesions. RF lesions were created in cadaveric porcine hearts and examined in a blood-filled field using a direct visualization catheter. Direct visualization of RF lesions was repeated in vivo using an ovine model. Lesions and interlesion gaps were clearly identifiable using the direct visualization catheter. It was possible to place lesions in proximity to anatomical landmarks and in relation to one another. Catheter-generated images correlated well with lesion appearance on gross examination. Direct catheter-based visualization is a feasible technique for guiding RF lesion placement, estimating lesion size, and identifying interlesion gaps. Future work is needed to correlate surface appearance with transmurality and electrical isolation.

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    Article: In situ optical mapping of voltage and calcium in the heart.
    Peter Lee, Fouad Taghavi, Ping Yan, Paul Ewart, Euan A Ashley, Leslie M Loew, Peter Kohl, Christian Bollensdorff, Christopher E Woods
    [show abstract] [hide abstract]
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    PLoS ONE 01/2012; 7(8):e42562. · 4.09 Impact Factor
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Keywords

blood-filled field
 
cadaveric porcine hearts
 
cardiac arrhythmias
 
cardiac tissue
 
Catheter-generated images correlated
 
correlate surface appearance
 
Direct catheter-based visualization
 
Direct visualization
 
direct visualization catheter
 
electrical isolation
 
fiber optic direct visualization catheter
 
gross examination
 
initial experience
 
interlesion gaps
 
lesion size
 
ovine model
 
place lesions
 
precise catheter navigation
 
RF lesion placement
 
RF lesions