Engineered heart tissue: high throughput platform for dissection of complex diseases.

Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Journal of Cardiovascular Translational Research (Impact Factor: 3.02). 09/2008; 1(3):232-5. DOI: 10.1007/s12265-008-9026-0
Source: PubMed


The polygenic nature of resistance/sensitivity of the heart to ischemia is generally accepted. Unfortunately, little is known about gene(s) involved in response to this insult. The goal of present study is to introduce new tool, engineered heart tissue (EHT), for accelerating positional cloning and for providing novel functional assays.

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