Start » Publications

A new approach for PEGylation of dendrimers.

Hemant Khambete, Surya P Gautam, C Karthikeyan, Suman Ramteke, N S Hari Narayana Moorthy, Piyush Trivedi

School of Pharmaceutical Sciences, Rajiv Gandhi Technical University, Airport Bypass Road, Gandhi Nagar, Bhopal (MP) 462 036, India.

Journal Article: Bioorganic & medicinal chemistry letters (impact factor: 2.65). 07/2010; 20(14):4279-81. DOI: 10.1016/j.bmcl.2010.03.100

Abstract

Dendrimers have emerged as one of the most interesting themes for researchers as a result of unique functional architecture and macromolecular characteristics. The reported methods of PEGylation are very time consuming and required multisteps for synthesis. In present work we have synthesized PEGylated polyamidoamine (PAMAM) dendrimers using epichlorohydrin as a linker. The PEGylated dendrimers were evaluated for color reaction UV, IR and NMR studies and compared with standard data.

Source: PubMed

Comments on this publication

ResearchGate members can add comments. Sign up now and post your comment!

Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Science & Research Jobs

View jobs

Keywords

interesting themes
 
IR
 
multisteps
 
PEGylated dendrimers
 
reported methods
 
standard data
 
unique functional architecture