Rapid detection of Trypanosoma cruzi in human serum by use of an immunochromatographic dipstick test.

Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Journal of clinical microbiology (Impact Factor: 4.16). 08/2010; 48(8):3003-7. DOI: 10.1128/JCM.02474-09
Source: PubMed

ABSTRACT We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of 366 (40.7%) and 171/366 (46.7%) samples tested positive by dipstick and serology, respectively. Dipstick sensitivity was calculated to be 84.8% (range between countries, 77.5 to 95%), and specificity was 97.9% (95.9 to 100%).

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May 16, 2014