Reducing Consumption of Sugar-Sweetened Beverages Is Associated With Reduced Blood Pressure A Prospective Study Among United States Adults

Program of Epidemiology, School of Public Health, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.
Circulation (Impact Factor: 14.43). 06/2010; 121(22):2398-406. DOI: 10.1161/CIRCULATIONAHA.109.911164
Source: PubMed

ABSTRACT Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The objective of this study was to determine the relationship between changes in SSB consumption and changes in BP among adults.
This was a prospective analysis of 810 adults who participated in the PREMIER Study (an 18-month behavioral intervention trial). BP and dietary intake (by two 24-hour recalls) were measured at baseline and at 6 and 18 months. Mixed-effects models were applied to estimate the changes in BP in responding to changes in SSB consumption. At baseline, mean SSB intake was 0.9+/-1.0 servings per day (10.5+/-11.9 fl oz/d), and mean systolic BP/diastolic BP was 134.9+/-9.6/84.8+/-4.2 mm Hg. After potential confounders were controlled for, a reduction in SSB of 1 serving per day was associated with a 1.8-mm Hg (95% confidence interval, 1.2 to 2.4) reduction in systolic BP and 1.1-mm Hg (95% confidence interval, 0.7 to 1.4) reduction in diastolic BP over 18 months. After additional adjustment for weight change over the same period, a reduction in SSB intake was still significantly associated with reductions in systolic and diastolic BPs (P<0.05). Reduced intake of sugars was also significantly associated with reduced BP. No association was found for diet beverage consumption or caffeine intake and BP. These findings suggest that sugars may be the nutrients that contribute to the observed association between SSB and BP.
Reduced consumption of SSB and sugars was significantly associated with reduced BP. Reducing SSB and sugar consumption may be an important dietary strategy to lower BP.
URL: Unique identifier: NCT00000616.

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Available from: Pao-Hwa Lin, Sep 29, 2015
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    • "A prospective cohort study( 86 ) indicated that higher consumption of SSB was associated with a higher risk of CHD. Additionally, a cross-sectional study( 34 ) and two other cohort studies( 87 , 88 ) positively associated a reduction in SSB consumption with a reduction of disease risk factors such as elevated blood pressure or weight gain. It should be mentioned, however, that relevant intervention studies with such risk factors as end-point are lacking. "
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    • "During the last decade, there has been an increasing number of published epidemiological and interventional studies on human populations linking the high consumption of sugar-sweetened beverages, enriched in simple sugars such as fructose and glucose, to the high prevalence of chronic metabolic and related cardiovascular diseases [1] [2] [3] [4]. These diseases include dyslipidemia [5] [6], gout [7], hypertension [8] [9], obesity [10] [11], insulin resistance [12] and type 2 diabetes mellitus [10] [13] [14] [15]. High energy intake, lack of adequate energy compensation through a proportional decrease in the amount of energy ingested as solid foods, and the special metabolism of fructose, have been reported to contribute to this possible causal association [2] [3]. "
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