Article

Patterning microfluidic device wettability using flow confinement

School of Engineering and Applied Sciences/Department of Physics, Harvard University, Cambridge, Massachusetts, USA.
Lab on a Chip (Impact Factor: 5.75). 07/2010; 10(14):1774-6. DOI: 10.1039/c004124f
Source: PubMed

ABSTRACT We present a simple method to spatially pattern the surface properties of microfluidic devices using flow confinement. Our technique allows surface patterning with micron-scale resolution. To demonstrate its effectiveness, we use it to pattern wettability to form W/O/W and O/W/O double emulsions.

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    • "A hydrophobic channel was prepared using a silane-coupling agent. Abate et al. (2010) proposed both hydrophobic and hydrophilic modifications of monolithic microchannels fabricated in PDMS using polyacrilic acid and photoreactive sol–gel mixture containing fluorosilane. Bauer et al. (2010) used sequential layer-bylayer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. "
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    ABSTRACT: Modification of the surfaces of polycarbonate (PC) with the use of a solution of tin (II) chloride renders them hydrophilic. The surface draping is stable against exposure to water and to alcohols. Exposure to alkanes reduces but does not diminish the effect. The method is compatible—in using the same solvent and temperature—with the hydrophobic modification of PC Jankowski et al. ( Lab Chip 11:748–752, 2011). The combination of these methods makes it possible to generate single and multiple monodisperse emulsions with the use of flow-focusing junctions in systems made in PC—material that is suitable for fabrication of multilayer, high throughput microfluidic devices.
    Microfluidics and Nanofluidics 06/2014; 14(5). DOI:10.1007/s10404-012-1090-8 · 2.67 Impact Factor
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    • "Microfluidic chips were fabricated by conventional soft lithography techniques [13]. To change the wettability of PDMS chips for double emulsion formation, the chips were coated following a two-step solegel coating procedure [22] "
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    Biomaterials 03/2013; 34(19). DOI:10.1016/j.biomaterials.2013.03.002 · 8.31 Impact Factor
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    • "A hydrophobic channel was prepared using a silane-coupling agent. Abate et al. (2010) proposed both hydrophobic and hydrophilic modifications of monolithic microchannels fabricated in PDMS using polyacrylic acid and photoreactive sol–gel mixture containing fluorosilane . Bauer et al. (2010) used sequential layer-by-layer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Modification of the surfaces of polycarbonate (PC) with the use of a solution of tin (II) chloride renders them hydrophilic. The surface draping is stable against exposure to water and to alcohols. Exposure to alkanes reduces but does not diminish the effect. The method is compatible—in using the same solvent and temperature—with the hydrophobic modification of PC (Jankowski et al. in Lab Chip 11:1151–1156, 2011). The combination of these methods makes it possible to generate single and multiple monodisperse emulsions with the use of flow-focusing junctions in systems made in PC—a material that is suitable for fabrication of multilayer, high-throughput microfluidic devices.
    Microfluidics and Nanofluidics 03/2012; 14(3-4). DOI:10.1007/s10404-012-1078-4 · 2.67 Impact Factor
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