Primary Malignant Mixed Müllerian Tumor of the Ovary

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Taiwanese journal of obstetrics & gynecology (Impact Factor: 0.99). 03/2010; 49(1):87-90. DOI: 10.1016/S1028-4559(10)60016-2
Source: PubMed


To present a case of malignant mixed müllerian tumor of the ovary, a rare and aggressive ovarian malignant tumor with poor prognosis.
A 52-year-old woman consulted our outpatient department with complaints of abdominal distention and a firm palpable mass over her lower abdomen. Physical examination and computerized tomography revealed cystic mass lesions on the bilateral adnexal areas. Ovarian cancer was suspected, so the patient underwent exploratory laparotomy. Optimal debulking surgery was performed, and final pathology revealed malignant mixed müllerian tumor of the ovary. Chemotherapy using ifosfamide and cisplatin were administered postoperatively, and adjuvant was also administered. After six cycles of chemotherapy, the patient is well with no signs of recurrence.
Ovarian malignant mixed müllerian tumor usually yields poor outcomes; hence, aggressive treatment with optimal debulking surgery followed by combination chemotherapy using ifosfamide and cisplatin may improve patient outcomes.

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