Isometric Quadriceps Strength in Women with Mild, Moderate, and Severe Knee Osteoarthritis

University of Michigan, Ann Arbor, 48109, USA.
American journal of physical medicine & rehabilitation / Association of Academic Physiatrists (Impact Factor: 2.01). 07/2010; 89(7):541-8. DOI: 10.1097/PHM.0b013e3181ddd5c3
Source: PubMed

ABSTRACT Quadriceps weakness is a common clinical sign in persons with moderate-to-severe osteoarthritis and results in physical disability; however, minimal data exist to establish whether quadriceps weakness is present in early stages of the disease. Therefore, our purpose was to determine whether quadriceps weakness was present in persons with early radiographic and cartilaginous evidence of osteoarthritis. Further, we sought to determine whether quadriceps strength decreases as osteoarthritis severity increases.
Three hundred forty-eight women completed radiologic and magnetic resonance imaging evaluation, in addition to strength testing. Anterior-posterior radiographs were graded for tibiofemoral osteoarthritis severity using the Kellgren-Lawrence scale. Scans from magnetic resonance imaging were used to assess medial tibiofemoral and patellar cartilage based on a modification of the Noyes scale. The peak knee extension torque recorded was used to represent strength.
Quadriceps strength (Nm/kg) was 22% greater in women without radiographic osteoarthritis than in women with osteoarthritis (P < 0.05). Quadriceps strength was also greater in women with Noyes' medial tibial and femoral cartilage scores of 0 when compared in women with Noyes' grades 2 and 3-5 (P < or = 0.05).
Women with early evidence of osteoarthritis had less quadriceps strength than women without osteoarthritis as defined by imaging.

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Available from: Riann M Palmieri-Smith, Jun 20, 2014
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    • "Muscle strength significantly contributes to knee joint loading during walking (Pandy and Andriacchi, 2010) with recent attention being focused on lower limb muscle strength among knee OA patients. While quadriceps muscle weakness is well documented among knee OA patients (Lewek et al., 2004b; Palmieri-Smith et al., 2010; Tan et al., 1995), hamstring muscle strength is less studied and the results are contradictory (Slemenda et al., 1998; Tan et al., 1995). New evidence suggests hip muscles to be weaker in knee OA patients than in controls (Costa et al., 2010; Hinman et al., 2010). "
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