Light diffusion in N-layered turbid media: Steady-state domain

Institut fur Lasertechnologien in der Medizin und Messtechnik, Helmholtzstrasse 12, Ulm, D-89081 Germany.
Journal of Biomedical Optics (Impact Factor: 2.86). 03/2010; 15(2):025003. DOI: 10.1117/1.3368685
Source: PubMed


We deal with light diffusion in N-layered turbid media. The steady-state diffusion equation is solved for N-layered turbid media having a finite or an infinitely thick N'th layer. Different refractive indices are considered in the layers. The Fourier transform formalism is applied to derive analytical solutions of the fluence rate in Fourier space. The inverse Fourier transform is calculated using four different methods to test their performance and accuracy. Further, to avoid numerical errors, approximate formulas in Fourier space are derived. Fast solutions for calculation of the spatially resolved reflectance and transmittance from the N-layered turbid media ( approximately 10 ms) with small relative differences (<10(-7)) are found. Additionally, the solutions of the diffusion equation are compared to Monte Carlo simulations for turbid media having up to 20 layers.

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    ABSTRACT: We deal with light diffusion in mismatched N-layered turbid media having a finite or an infinitely thick N'th layer. We focus on time-resolved light propagation in both the frequency and time domains. Based on our results for the steady-state domain, solutions of the N-layered diffusion equations in the frequency and time domains are obtained by applying the Fourier transform technique. Different methods for calculation of the inverse Fourier transform are studied to validate the solutions, showing relative differences typically smaller than 10(-6). The solutions are compared to Monte Carlo simulations, revealing good agreement. Finally, by applying the Laplace and Fourier transforms we derive a fast ( approximately 1 ms) and accurate analytical solution for the time domain reflectance from a two-layered turbid medium having equal reduced scattering coefficients and refractive indices in both layers.
    Journal of Biomedical Optics 03/2010; 15(2):025002. DOI:10.1117/1.3368682 · 2.86 Impact Factor
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    ABSTRACT: This paper is the second of two dealing with light diffusion in a turbid cylinder. The diffusion equation was solved for an N-layered finite cylinder. Solutions are given in the steady-state, frequency, and time domains for a point beam incident at an arbitrary position of the first layer and for a circular flat beam incident at the middle of the cylinder top. For special cases the solutions were compared to other solutions of the diffusion equation showing excellent agreement. In addition, the derived solutions were validated by comparison with Monte Carlo simulations. In the time domain we also derived a fast solution ( approximately 10ms) for the case of equal reduced scattering coefficients and refractive indices in all layers.
    Optics Express 04/2010; 18(9):9266-79. DOI:10.1364/OE.18.009266 · 3.49 Impact Factor
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