Image Findings of Patients with H1N1 Virus Pneumonia and Acute Respiratory Failure
Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim, Germany. Academic radiology
(Impact Factor: 1.75).
06/2010; 17(6):681-5. DOI: 10.1016/j.acra.2010.03.013
The aim of this study was to assess the findings of chest radiography and high-resolution computed tomography in patients requiring intensive care unit treatment for severe H1N1 virus pneumonia.
In 2009, 10 patients required treatment in an intensive care unit for confirmed H1N1 pneumonia. All patients underwent chest radiography and high-resolution computed tomography. All 10 patients required mechanical ventilation because of respiratory failure. Nine patients presented with severe acute respiratory distress syndrome, and one patient died. Four patients underwent extracorporeal membrane oxygenation (ECMO) therapy. The results of chest radiography and high-resolution computed tomographic scans of these patients were systematically analyzed.
The mean age of all patients was 44.1 +/- 12.3 years. All 10 patients showed abnormal results on chest radiography. The radiographic abnormalities were bilateral and multifocal in 10 patients. The predominant radiographic findings were consolidations (n = 9), ground-glass opacities (n = 8), and reticular opacities (n = 2). The most frequent computed tomographic findings at presentation consisted of bilateral ground-glass opacities (n = 9), pleural effusion (n = 9), areas of consolidation (n = 8), interstitial marking (n = 8), and crazy paving (n = 4). All patients undergoing ECMO therapy showed extensive bilateral ground-glass opacities, multifocal areas of consolidation, and crazy paving. Pleural effusion was present in three of four patients undergoing ECMO therapy.
Patients requiring treatment in an intensive care unit for severe H1N1 pneumonia are at high risk for developing acute respiratory distress syndrome and frequently require ECMO therapy.
Available from: Edson Marchiori
- "A crazy-paving pattern, in which ground-glass opacities are associated with septal thickening, has been reported in few cases in the literature.( 22
) In our study, 15% of the patients showed this pattern. Septal thickening without ground-glass opacities was a mild secondary finding, being observed in only 4 patients (6%). "
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ABSTRACT: To describe aspects found on HRCT scans of the chest in patients infected with the influenza A (H1N1) virus.
We retrospectively analyzed the HRCT scans of 71 patients (38 females and 33 males) with H1N1 infection, confirmed through laboratory tests, between July and September of 2009. The HRCT scans were interpreted by two thoracic radiologists independently, and in case of disagreement, the decisions were made by consensus.
The most common HRCT findings were ground-glass opacities (85%), consolidation (64%), or a combination of ground-glass opacities and consolidation (58%). Other findings were airspace nodules (25%), bronchial wall thickening (25%), interlobular septal thickening (21%), crazy-paving pattern (15%), perilobular pattern (3%), and air trapping (3%). The findings were frequently bilateral (89%), with a random distribution (68%). Pleural effusion, when observed, was typically minimal. No lymphadenopathy was identified.
The most common findings were ground-glass opacities and consolidations, or a combination of both. Involvement was commonly bilateral with no axial or craniocaudal predominance in the distribution. Although the major tomographic findings in H1N1 infection are nonspecific, it is important to recognize such findings in order to include infection with the H1N1 virus in the differential diagnosis of respiratory symptoms.
Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 06/2013; 39(3). DOI:10.1590/S1806-37132013000300009 · 1.02 Impact Factor
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ABSTRACT: A portable data acquisition system using pressure sensors, built to measure pressures between bony prominences of each foot and the shoe, is described. Data acquisition algorithms for extracting peak pressure, area under the curve, heel strike to pushoff time, and center of pressure are discussed. Sample results of an analysis from 2-h tests on ten subjects are presented, revealing interesting behavior of the pressure changes under the foot and the gait. The results can be used to provide feedback to subjects who have lost sensation from the feet and ankles
European journal of radiology 10/2010; 80(2):573-5. DOI:10.1016/j.ejrad.2010.10.004 · 2.37 Impact Factor
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