Pulp response to resin-modified glass ionomer and calcium hydroxide cements in deep cavities: A quantitative systematic review
ABSTRACT To quantitatively determine whether the pulp response to resin-modified glass ionomer cements placed in deep cavities differs from that generated by calcium hydroxide cement.
Five databases were searched for articles up to 31 May 2009.
Inclusion criteria: titles/abstracts relevant to topic; published in English; two-arm longitudinal in vivo trial; containing computable dichotomous datasets for test and control group. Exclusion criteria: not all entered subjects accounted for at the end of the trial; subjects of both groups not followed up in the same way; trial on animal tissue.
One randomized and five non-randomized control trials, reporting on 1 and 17 datasets, respectively, were accepted. From non-randomized trials, the Relative Risk with 95% Confidence Interval of 13 datasets showed no statistically significant differences (p>0.05) and 4 showed a statistically significant difference between both materials. Meta-analysis of datasets from these trials found no difference between the inflammatory cell response after 30 days (0.87; 95%CI 0.59-1.26; p=0.46); 38% less inflammatory cell response with calcium hydroxide after 60 days (0.62; 95%CI 0.50-0.76; p<0.00001); higher number of intact odontoblasts beneath restored cavities after 381 days (0.56; 95%CI 0.38-0.82; p=0.0008). The results from the randomized control trial (1.40; 95%CI 0.92-2.14; p=0.11) indicated no difference in clinically identifiable pulp symptoms after two years. All trials showed limited internal validity due to selection bias.
No conclusive statement about the superiority of either type of material can yet be made. Further high-quality randomized control trials are needed.
SourceAvailable from: Kundabala Mala
Article: Biominerals in restorative dentistry[Show abstract] [Hide abstract]
ABSTRACT: Restorative treatment strategies are being developed to repair and replace lost tooth structures and surrounding bone. The teeth under goes a constant cycle of demineralization and remineralization, but this natural remineralization process is inadequate to prevent progression of dental caries. Hence there is a need to supplement the tooth with a biomaterial which is bio inert or bioactive to remineralize, repair or regenerate the tissues of tooth. Calcium hydroxide is considered the gold standard material for repair of dentin, which is presently being replaced by materials with superior properties such as mineral trioxide aggregate. Biomaterials such as calcium phosphate cements are been advocated as bone substitute material because of properties such as biocompatibility, osteoconductivity and moldability. This review deals with the physiochemical properties of some of the biomineral based biomaterials which are currently used for repair, replacement or regeneration of hard tissues of teeth and bone.
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ABSTRACT: In this research, the effects of calcium hydroxide addition to zinc polycarboxylate cements have been studied on microstructural properties, setting time, pH changes and compressive strength. The results indicated that the setting time of the resultant cements increased with increase in the calcium hydroxide content to the cement matrix. Moreover, the compressive strength of the set cement optimally increased with addition of 5 wt% calcium hydroxide and then decreased by addition of 10 and 15 wt% calcium hydroxide. The effect of calcium hydroxide content on the properties of the set cements however was somewhat more complex, and a variable correlation was observed between the initial setting time and compressive strength. The prepared cements could be useful in surgical sites that are not freely accessible when using minimally invasive techniques. This is a preliminary study and more detailed work is required to evaluate other properties of this class of material.Ceramics International 12/2013; 39(8):9525-9532. DOI:10.1016/j.ceramint.2013.05.071 · 2.09 Impact Factor
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ABSTRACT: The purpose of this study was to evaluate the inflammatory and cure events of acid-based reactions using glass ionomer cement used for cementation of crowns, bridges, onlays and orthodontic bands implanted in subcutaneous tissue, at different time intervals. A total of 48 male Wistar rats were used, distributed into 4 groups (n = 12), as follows: Group C (control, polyethylene), Group ME (Meron), Group KC (Ketac Cem) and Group PR (Precedent). The animals were sacrificed after time intervals of 7, 15 and 30 days, and their tissues were analyzed under an optical microscope for such events as inflammatory infiltrate, edema, necrosis, granulation tissue, multinucleated giant cells, young fibroblasts and collagen. The results was assessed using Kruskal-Wallis and Dunn's tests (p < 0.05). In the initial period, intense inflammatory infiltrate was observed for all the materials with no significant difference among them (p = 0.104). Groups PR and KC showed significant difference in relation to Group C, at 7 days (p = 0.025) and 15 days (p = 0.006). Edema and giant cells were more expressive in Group ME, differing significantly from Groups C (p = 0.023) and KC (p = 0.039), respectively, at 7 days. Group ME showed a statistically significant difference in relation to Groups PR and KC for the presence of young fibroblasts (p = 0.009) and for collagen (p = 0.002), at 7 days. Within the limits of this in vivo study, Precedent and Ketac Cem glass ionomer cements showed better tissue healing with a greater number of fibroblasts and collagen, as compared to Meron.Brazilian oral research 03/2014; 28(1). DOI:10.1590/S1806-83242014.50000003 · 0.77 Impact Factor