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Understanding Cancer Cell Motility and Interactions with the Extracellular Matrix

DOI:handle/1774.2/34118
Source: OAI

ABSTRACT The enzyme Transglutaminase is used as a novel method of increasing the stiffness of collagen gel without affecting other characteristics. This discovery has allowed for a more accurate analysis of cancer cell motility in a stiffer ECM leading to a potential understanding of the mechanism behind tumor metastasis. Johns Hopkins University, Office of the Provost

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