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BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia.

IRCCS Santa Lucia Foundation, Department of Clinical and Behavioural Neurology, Via Ardetina, 306, 00179 Rome, Italy.
European Psychiatry (Impact Factor: 3.21). 10/2010; 25(6):311-3. DOI: 10.1016/j.eurpsy.2009.10.008
Source: PubMed

ABSTRACT Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.

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