Article

An Update on Vitamin E, Tocopherol and Tocotrienol-Perspectives

Department of Drug Science and Technology, University of Torino, via Pietro Giuria 9, Torino, Italy.
Molecules (Impact Factor: 2.42). 04/2010; 15(4):2103-13. DOI: 10.3390/molecules15042103
Source: PubMed

ABSTRACT Vitamin E, like tocotrienols and tocopherols, is constituted of compounds essential for animal cells. Vitamin E is exclusively synthesized by photosynthetic eukaryotes and other oxygenic photosynthetic organisms such as cyanobacteria. In order to prevent lipid oxidation, the plants mainly accumulate tocochromanols in oily seeds and fruits or in young tissues undergoing active cell divisions. From a health point of view, at the moment there is a great interest in the natural forms of tocochromanols, because they are considered promising compounds able to maintain a healthy cardiovascular system and satisfactory blood cholesterol levels. Some evidence suggests that the potency of the antioxidant effects may differ between natural or synthetic source of tocochromanols (vitamin E).

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    • "Vitamin E is a generic name for both tocopherols and tocotrienols. They are structurally similar but tocotrienols differ from tocopherols in having an unsaturated phytyl side chain (Colombo, 2010). Both tocopherols and tocotrienols comprise a, b, c and d forms, depending on the number and position of methyl groups on the chromanol ring. "
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    ABSTRACT: The protective effects of oil palm vitamin E and phenolics against atherosclerosis, either singly or in combination, were studied in an atherogenic rabbit model. Rabbits were either fed atherogenic diet only (CTR), or atherogenic diet with vitamin E (VIT E), or atherogenic diet with oil palm phenolics (OPP), or atherogenic diet with both vitamin E and oil palm phenolics (VIT E + OPP). Results from lipid profile and antioxidant analyses were not signif-icantly different between groups (p > 0.05). However, fibrous plaques were associated with the CTR group (8.90 ± 5.41%) and these were significantly less (p < 0.05) in the VIT E (2.88 ± 2.01%) and OPP (1.48 ± 4.45%) groups. Fibrous plaques were not detected at all in the VIT E + OPP group. Our findings suggest that oil palm vitamin E and oil palm phenolics individually inhibited atherosclerotic lesion development. However, oil palm vitamin E in combination with oil palm phenolics provided the highest protective effect against devel-opment of atherosclerotic lesions. Ó 2014 Published by Elsevier Ltd.
    Journal of Functional Foods 01/2014; 7. DOI:10.1016/j.jff.2014.01.002 · 4.48 Impact Factor
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    • "L'huile de tournesol bénéficie d'une bonne image, en raison de sa composition équilibrée en acides gras insaturés, cependant sa trop forte teneur en acides gras oméga-6 pourrait la désavantager pour une utilisation principale en alimentation, car notre alimentation est déjà déséquilibrée en faveur des oméga-6 (Blouin et al., 2006). Un nouvel intérêt pour cette huile pourrait provenir de sa grande richesse en composés mineurs, notamment en tocophérols (vitamine E), intéressants tout autant pour leur effet santé (Colombo, 2010) que pour leur action antirancissement de l'huile (Seppanen et al., 2010). Les phytostérols sont aussi présents en quantité importante. "
    OCL - Oleagineux Corps Gras Lipides 05/2010; 17(3):171-184. DOI:10.1051/ocl.2010.0314
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