Normal values for longitudinal function of the right ventricle in healthy women >70 years of age

Medizinische Klinik II, Kardiologie und Angiologie, Berufsgenossenschaftliche Universitätsklinik Bergmannsheil GmbH, Bürkle-de-la-Camp-Platz 1, D-44789 Bochum, Germany.
European Heart Journal – Cardiovascular Imaging (Impact Factor: 2.65). 04/2010; 11(8):725-8. DOI: 10.1093/ejechocard/jeq053
Source: PubMed


The application of tricuspid annular plane systolic excursion (TAPSE) as an additional echocardiographic tool to analyse right ventricular (RV) systolic function has been recently established and two-dimensional-guided M-mode measurements of systolic long axis function of the RV are simple, repeatable, and highly reproducible. However, rare data are available on normal values. We aimed to analyse normal values in healthy women >70 years of age.
In a cross-sectional survey, we investigated a cohort of randomly selected, non-hospitalized women >70 years of age. History of myocardial infarction, valvular heart disease, and diastolic dysfunction were exclusion criteria. In order to rule out left ventricular or RV dysfunction, a normal left ventricular ejection fraction and normal values of B-type natriuretic peptide (BNP) were necessary prior to study inclusion. A detailed echocardiographic examination was performed. A total of 80 participants were included (mean age 75 +/- 2.6 years). Mean left ventricular ejection fraction was 63.8 +/- 5.7%. Tissue Doppler derived mean E/E' ratio was 10 +/- 2.3. Mean right atrial diameter was 31.3 +/- 4.7 mm. Mean values for RV outflow tract and RV dimension were 27.3 +/- 3.6 and 28.8 +/- 3.7 mm, respectively. Mean TAPSE was 23.7 +/- 3.5 mm. Mean value of BNP was normal (42.5 +/- 35.7 pg/mL).
In women >70 years of age without heart failure, structural heart disease, and neurohormonal activation, normal TAPSE values are approximately 24 mm.

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    • "Values were averaged for each patient. Right atrial and ventricular dimensions were measured in apical 4-chamber and parasternal short-axis views, tricuspid annular plane systolic excursion (TAPSE) was measured by M-mode recordings from the apical 4-chamber view with the cursor placed at the free wall of the tricuspid valve [12]. Peak velocities of early (E) and late (A) diastolic filling and deceleration time were derived from transmitral Doppler profile [2]. "
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