Article

Recurrent phyllodes tumor of the vulva: a case report with review of diagnostic criteria and differential diagnosis.

Department of Obstetrics and Gynecology, UT Southwestern Medical Center at Dallas, Texas, U SA.
International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists (Impact Factor: 1.63). 05/2010; 29(3):294-7. DOI: 10.1097/PGP.0b013e3181c14a8c
Source: PubMed

ABSTRACT Phyllodes tumor of the vulva is extremely rare with only 6 cases reported in the literature. We report a case of recurrent phyllodes tumor of the vulva in a 39-year-old woman. The tumor showed biphasic morphology with a typical leaf-like pattern and a cellular stroma with rare mitosis. Expression of estrogen receptors, progesterone receptors mammoglobin, and BRST-2 was shown in the epithelial component. Review of literature with emphasis on diagnostic features and differential diagnosis are discussed.

0 Followers
 · 
64 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: We present a hitherto unreported case of vulvar phyllodes tumor which displayed morphologically malignant stroma including rhabdomyosarcomatous cellular elements. Clinically, the 61-year-old patient is free of recurrence 1 year after wide local excision.
    International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists 03/2011; 30(2):198-202. DOI:10.1097/PGP.0b013e3181f45f58 · 1.63 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Carcinosarcoma is exceedingly rare in the vulva. We describe a case of carcinosarcoma in a 67-year-old female patient who presented with recent enlargement and pain of a vulval nodule noted for 15 years. The excised tumor showed intermixed carcinomatous (adenocarcinoma and anaplastic carcinoma) and sarcomatous elements (osteosarcoma, chondrosarcoma, and leiomyosarcoma), which focally merged with several lobules of typical eccrine spiradenoma. The inguinal lymph nodes showed metastasis of the carcinomatous component only. This case represents the first reported case of vulval carcinosarcoma of the skin adnexal origin, and has to be distinguished from sarcomatoid carcinoma of epidermal origin because of a probable more aggressive behavior.
    International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists 04/2011; 30(3):301-5. DOI:10.1097/PGP.0b013e3182055a3d · 1.63 Impact Factor