Article

Pigmented villonodular synovitis of the spine : report of a lumbar case

Marmara University, Faculty of Medicine, Department of Neurosurgery, Altunizade, Istanbul, Turkey.
Turkish neurosurgery (Impact Factor: 0.53). 04/2010; 20(2):251-6. DOI: 10.5137/1019-5149.JTN.1590-08.3
Source: PubMed

ABSTRACT Pigmented villonodular synovitis is a benign proliferative disease of the synovial structures. This disease is most commonly seen in the extremities, and spinal involvement is extremely rare. In the relevant literature, 53 cases have been reported. We present a 66-year-old female patient with a long history of back pain, which progressed and radiated to the left leg over a period of 2 months. The patient also had a mass in the lumbar region on the grounds of spinal degenerative changes. Following gross total excision, the diagnosis was established by histopathology. In this report, we present our experience and discuss our neuroradiological and clinical findings.

Download full-text

Full-text

Available from: Suheyla Uyar Bozkurt, Jul 14, 2014
0 Followers
 · 
140 Views
 · 
51 Downloads
  • Source
    • "Neurological signs differ according to the level of the tumoral mass. A patient admitted with chronic back pain and acute progression of neurological signs should alert the physician about tumoral and infectious lesions, among which PVNS involves a little proportion [5] [8] "
    [Show abstract] [Hide abstract]
    ABSTRACT: Pigmented villonodular synovitis (PVNS) is a proliferative benign lesion originating from the synovium and commonly affects large joints of the extremities. PVNS can arise from any synovium in the whole body and rarely affects the zygapophyseal joints of the spine. Spinal PVNS is diagnosed mostly after resection of the mass. In our case we present a 22-year-old male patient showing progressive spastic paraparesis with insidious onset of back pain and difficulty of walking in a relatively short period of 1 month. After gross excision of the mass, diagnosis was established through histopathology. Two years of follow-up period reveals complete resolution of the patient's complaints and no recurrence on radiologic images.
    09/2013; 2013(6):870324. DOI:10.1155/2013/870324
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction Pigmented Villonodular synovitis (PVNS) is a rare vertebral pathology--around 50 reports, only 3 concerning C1-C2 location. Case Report A 64-year-old man, submitted to a right nephrectomy for a clear cell carcinoma, presented with an asymptomatic osteolytic C1-C2 lesion. Even though the diagnosis of metastatic disease was the most probable, the presence of a solitary lesion without other osseous or systemic localization and the predicted low risk of recurrence imposed a surgical biopsy. A pigmented villonodular synovitis diagnosis was made, a rare vertebral pathology--around 50 reports, only 3 concerning C1-C2 location. No further treatment was assigned precluding the iatrogenic consequences of empirical treatments based on clinical diagnosis with no histopathological support. The patient remains stable at 18 months of follow-up. Conclusion A large differential diagnosis should be made when the typical findings for metastatic disease are absent precluding the iatrogenic consequences of empirical treatments based on clinical diagnosis with no histopathological support.
    European Spine Journal 06/2014; 24(S4). DOI:10.1007/s00586-014-3396-6 · 2.47 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Pigmented villonodular synovitis (PVNS) is a benign proliferative joint disease with an uncertain etiology that uncommonly involves the spine. We present a case of PVNS involving the lumbar spine. A 38-year-old male developed back pain and pain in both legs caused by a mass in the L4 region of the right lamina. After gross total tumor removal, the symptoms improved. The pathological finding was synovial hyperplasia with accumulation of hemosiderin-laden macrophages. He was diagnosed with PVNS and experienced no recurrence for up to 2 years after surgery. In this report, we review the previous literature and discuss etiology, clinical manifestations, diagnosis, and treatment.
    Journal of Korean Neurosurgical Society 09/2014; 56(3):272-7. DOI:10.3340/jkns.2014.56.3.272 · 0.52 Impact Factor
Show more