Enzyme technology for precision functional food ingredient processes
BioProcess Engineering Center, Department of Chemical and Biochemical Engineering, Technical University of Denmark, Lyngby, Denmark.Annals of the New York Academy of Sciences (Impact Factor: 4.38). 03/2010; 1190(1):126-32. DOI: 10.1111/j.1749-6632.2009.05255.x
A number of naturally occurring dietary substances may exert physiological benefits. The production of enhanced levels or particularly tailored versions of such candidate functional compounds can be targeted by enzymatic catalysis. The recent literature contains examples of enhancing bioavailability of iron via enzyme-catalyzed degradation of phytate in wheat bran, increasing diacyl-glycerol and conjugated linoleic acid levels by lipase action, enhancing the absorption of the citrus flavonoid hesperetin via rhamnosidase treatment, and obtaining solubilized dietary fiber via enzymatic modification of potato starch processing residues. Such targeted enzyme-catalyzed reactions provide new invention opportunities for designing functional foods with significant health benefits. The provision of well-defined naturally structured compounds can, moreover, assist in obtaining the much-needed improved understanding of the physiological benefits of complex natural substances.
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- ". The major industrial enzyme applications [Aguilar et al., 2007; Araujo et al., 2008; Ba et al., 2013; Brady et al., 2004; Casas-Godoy et al., 2012; Choct, 2006; Demuner et al., 2011; Fendri et al., 2012; Kirk et al., 2002; Huisman & Collier, 2013; Jemli et al., 2007; Kalantzi et al., 2008; Khan, 2013; Rhimi et al., 2009; Sanchez & Demain, 2011; Meyer, 2010). "
ABSTRACT: Abstract Enzymes are widely applied in various industrial applications and processes, including the food and beverage, animal feed, textile, detergent and medical industries. Enzymes screened from natural origins are often engineered before entering the market place because their native forms do not meet the requirements for industrial application. Protein engineering is concerned with the design and construction of novel enzymes with tailored functional properties, including stability, catalytic activity, reaction product inhibition and substrate specificity. Two broad approaches have been used for enzyme engineering, namely, rational design and directed evolution. The powerful and revolutionary techniques so far developed for protein engineering provide excellent opportunities for the design of industrial enzymes with specific properties and production of high-value products at lower production costs. The present review seeks to highlight the major fields of enzyme application and to provide an updated overview on previous protein engineering studies wherein natural enzymes were modified to meet the operational conditions required for industrial application.Critical Reviews in Biotechnology 11/2014; 6:1-13. DOI:10.3109/07388551.2014.950550 · 7.18 Impact Factor
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ABSTRACT: This paper proposes a model to describe the effect of recycled aggregate (RA) on the chloride diffusion in recycled aggregate concrete (RAC). In this study, RAC is modeled in mesoscope as a five-phase composite material by considering the old and new interfacial transition zones (ITZs) as interphases, and the new mortar, old attached mortar and original aggregate as continuous phases. Based on the multiphase theory, new theoretical equations are derived to calculate the effective chloride diffusivity (Deff ) in the modeled RAC. Using the finite element method (FEM) simulation, a parametric study has been undertaken to understand the effects of the RA volume fraction (Fra ), the RA shapes, the boundary conditions, the adhesive rate of the old adhered mortar (Rrm ) and the thickness of the ITZ (T ITZ) on the chloride diffusivity in RAC. It is concluded that the discrepancy between the chloride diffusivities of different phases may remarkably complicate the chloride diffusion behavior in the modeled RAC. For the same volume of RAC, Deff decreases with the increase of Fra , but increases with Rrm and T ITZ. The RA shape also influences the chloride concentration. Furthermore, the values of Deff calculated from theoretical equation and from the FEM are in reasonable agreement.Construction and Building Materials 04/2012; 29. DOI:10.1016/j.conbuildmat.2011.08.073 · 2.30 Impact Factor
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ABSTRACT: Iron deficiency is one of the most common nutritional deficiencies worldwide, in both developing and developed regions. Although the aetiology of iron deficiency and resultant anaemia may be multifaceted, inadequate iron intakes, poor iron absorption and disease status may all be underlying causes. Whilst nutrition and supplement interventions may go some way towards improving iron status in ‘at-risk’ populations, their efficacy can be questioned. New approaches, including food-based strategies, may be an alternative means of improving the iron status and health of the public sectors. Economically, food-based approaches may also be more cost-effective than iron supplements. This paper aims to discuss how the food industry may play an important role in improving the iron status of public sectors, helping to prevent iron deficiency and need for tablet-based iron supplements.International Journal of Food Science & Technology 11/2010; 45(12):2443 - 2448. DOI:10.1111/j.1365-2621.2010.02431.x · 1.38 Impact Factor
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