Insomnia and Sleep Duration in a Large Cohort of Patients With Major Depressive Disorder and Anxiety Disorders
ABSTRACT Disturbed sleep has a high impact on daily functioning and has been correlated with psychopathology. We investigated the extent to which insomnia and sleep duration were associated with both current and remitted depressive and anxiety disorders in a large-scale epidemiologic study, taking sociodemographics, health factors, and medication use into account.
Data of 2,619 individuals from the Netherlands Study of Depression and Anxiety (NESDA) were analyzed. Psychopathology was classified as no, current, or remitted DSM-IV-based diagnosis of major depressive or anxiety disorder. Outcome measures were insomnia (Women's Health Initiative Insomnia Rating Scale score >or= 9) and sleep duration (<or= 6 hours, 7-9 hours, >or= 10 hours). Baseline measurement was conducted between September 2004 and February 2007.
Both current and remitted depressive disorder and current anxiety disorder were associated with insomnia and short sleep duration with odds ratios (ORs) for insomnia ranging from 1.42 to 3.23 and for short sleep duration ranging from 1.41 to 2.53. Associations were stronger for current than for remitted diagnoses and stronger for depressive than for anxiety disorders. Also long sleep duration was associated with current depressive disorder and anxiety disorders (OR range, 1.53-2.66). Sociodemographic factors, health indicators, and psychotropic medication use did contribute to sleep outcomes but could not explain much of the psychopathology and sleep associations.
Depressive disorder-but also anxiety disorder-is strongly associated with sleep disturbances. Insomnia and short sleep duration persist after remittance of these disorders, suggesting that these are residual symptoms or possibly trait markers. Also, long sleep duration is associated with current depressive or anxiety disorders.
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ABSTRACT: Background: An adequate sleeping pattern recovers physical and mental wellbeing and improves mood. Aim: To determine the association between quality of life and quantity of sleep in older people living in Santiago and Viña del Mar, Chile. Material and Methods: The Spanish versions of the Health Promoting Lifestyles survey and the Pittsburgh Sleep Quality Index were answered by 975 non-disabled participants aged 70.7 ± 7.4 years (61% females). Results: Older adults who slept < 7.0 or > 8.5 hours (h) per night were at higher risk of having lower quality of life scores for all sub-domains, compared with those that slept 7.0 to 8.5 h per night. Conclusions: A normal sleep pattern in older adults is associated with a better quality of life perception.Revista medica de Chile 01/2014; 142:1371-1376. · 0.37 Impact Factor
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ABSTRACT: Objectives: Given the persistence of Post Traumatic Stress Disorder (PTSD) and its major impact on everyday life, it is important to identify effective treatments. In additional to pharmacological treatments, psychotherapeutic treatments are also highly effective. The aim of the present study was to investigate, among a sample of patients suffering from PTSD, the influence of an additional cognitive behavioral therapy (CBT) intervention on their symptoms of PTSD, depression and anxiety, and autobiographical memory. Methods: A total of 40 patients suffering from PTSD (mean age: M = 31.64 years; 78.6% female patients) and under psychopharmacological treatment were randomly assigned to an intervention or control condition. The intervention consisted of 10 group sessions (one 60-90 minute session per week) of CBT. At baseline and 10 weeks later, a series of self-rating and experts’ rating questionnaires were completed. Results: Over time, symptoms of PTSD depression, and anxiety decreased; however, greater improvement was observed in the experimental than the control condition. Likewise, as a general pattern of results, memory performance improved over time, though again this improvement was greater in the experimental condition. Conclusions: Compared to a control condition, additional CBT improves the treatment of PTSD, with respect to both symptoms and autobiographical memory.Neuropsychiatric Disease and Treatment 02/2015; 11. DOI:10.2147/NDT.S79581 · 2.15 Impact Factor