Single- vs. multiple-item instruments in the assessment of quality of life in patients with advanced cancer.
ABSTRACT Although multidimensional instruments are usually used to measure quality of life in advanced cancer patients, recent research suggests that single-item assessments can provide a reliable measure. Using the Functional Assessment of Cancer Therapy-General (FACT-G) instrument as a gold standard, we assessed the performance of the Edmonton Symptom Assessment System "feeling of well-being" (ESAS WB) item. We reviewed the data from 213 patients enrolled in six clinical trials. We determined the association between baseline ESAS WB and FACT-G total and subscale domain scores (Physical Well-being [PWB], Social/Family Well-being [SWB], Emotional Well-being [EWB], and Functional Well-being [FWB]. We also calculated the association between baseline (T1) and second (T2) observations of ESAS WB and of FACT-G total score. In addition, we predicted the change in FACT-G predicted by the ESAS WB score using regression analysis. Mean age was 60 (SD 12) years and 48% were female. The Spearman correlation coefficient of ESAS WB and FACT-G was -0.48 (P<0.0001). Correlations with FACT-G subscale domains were also highly significant, except for the SWB domain (P=0.08). The Pearson correlation coefficient for T1-T2 in ESAS WB and FACT-G for 146 patients was -0.36 (P<0.0001). The change in ESAS WB corresponding to FACT-G published minimally important difference was -0.24 for 3, -1.55 for 5, and -2.87 for 7, respectively. These results suggest that the single-item measure ESAS WB best reflects the total score on the FACT-G and PWB, EWB, and FWB domains but not on the SWB domain.
- SourceAvailable from: Loren Toussaint[Show abstract] [Hide abstract]
ABSTRACT: Objective: This study examined the prospective association between unforgiveness and self-reported physical health and potential positive psychological mediators of this association. Design: Participants were a national sample of 1024 USA's adults of ages 66 years and older. Data were collected at two time points separated by three years. Main Outcome Measures: Measures of trait unforgiveness, self-rated physical health, socio-demographics, health behaviours and positive psychological traits (e.g. life satisfaction, self-esteem) were included in a comprehensive survey known as the 'Religion, Aging, and Health Survey.' Results: The results indicated that unforgiveness was prospectively associated with declines in self-reported physical health three years later, and poor initial self-reported health status did not predict increases in unforgiveness across time. Furthermore, the prospective association of unforgiveness with self-reported health was mediated by a latent positive psychological traits variable. Conclusion: These results confirm cross-sectional findings suggesting that unforgiveness is related to health. The present study also suggests that unforgiveness has a prospective, but not reciprocal, association with self-reported physical health. Unforgiveness may have its association with self-reported physical health through its interruption of other positive traits that typically confer health benefits.Psychology & Health 11/2013; · 1.95 Impact Factor
Conference Paper: The modelling of F0 contours[Show abstract] [Hide abstract]
ABSTRACT: There is interest in speech research for a model that captures all the relevant features of the intonation contour. Such a model is capable of generating natural intonation contours from the minimum amount of input data. Much of the work on this type of modelling has been performed for Dutch (1). Their model gave a result that was "perceptually-equivalent" to an original contour. A deficiency in this type of description is that perceptually-equivalent is not synonymous with natural. Although a contour may be perceived as being equivalent to an original, it may not necessarily be indistinguishable in an auditory sense from an original intonation contour. The model described in this paper has the capacity to produce intonation contours for English that are perceptually-equivalent and also auditorily indistinguishable from the original. The model consists of the concatenation of contour segments; each segment being modelled by a quadratic equation.Acoustics, Speech, and Signal Processing, IEEE International Conference on ICASSP '82.; 06/1982
- Journal of palliative medicine 12/2011; 14(12):1281-2. · 1.84 Impact Factor