Article

Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans

Correspondence to Dr S Louis Bridges Jr, University of Alabama at Birmingham, 1530 3rd Avenue South, 178C SHEL, Birmingham, Alabama 35294-2182, USA
Annals of the rheumatic diseases (Impact Factor: 10.38). 04/2010; 69(4):625-6. DOI: 10.1136/ard.2009.113183
Source: PubMed
Download full-text

Full-text

Available from: Leigh Callahan, Sep 03, 2015
0 Followers
 · 
98 Views
 · 
24 Downloads
  • [Show abstract] [Hide abstract]
    ABSTRACT: Data skew can result in load imbalance in parallel hash join. We introduce a new term, solid data skew, and classify data skew into plane and solid categories in this paper. The existing algorithms consider plane data skew only thus not adequate to approach solid data skew problem. A dynamic approach for handling solid data skew problem is proposed. It assigns join subtasks to processors during runtime using a method based on the estimation of execution time required for the computation
    TENCON '93. Proceedings. Computer, Communication, Control and Power Engineering.1993 IEEE Region 10 Conference on; 11/1993
  • [Show abstract] [Hide abstract]
    ABSTRACT: Guided and radiation modes in a nonlinear planar graded-index waveguide are considered. The numerical results (effective refractive index versus mode power and mode field distributions) are presented. The intensity-dependent cutoff value for the radiation modes is observed. A dark fundamental wave at the smooth interface of the nonlinear substrate and waveguide region is studied. The discrete spectrum of the solutions that describe quasi-guided modes with a constant (nonzero) value of the field in the substrate is found.
    Cytokine 07/1996; 128(4):223-228. DOI:10.1016/0030-4018(96)00104-6 · 2.87 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Association studies of over 1 million SNPs capturing most of the human genome common variation became possible thanks to the information provided by the HapMap International project and the development of high-throughput genotyping technologies at accessible prices. Genome-wide scans analyzing thousands of individuals have now identified most if not all of the major genes involved in susceptibility for several systemic autoimmune diseases. In particular, results for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic sclerosis (SSc) are reviewed here. While most genes are shared between diseases, few seem to be unique reflecting that we still are long before knowing all genes, their interactions with other genes and the environment and their impact on biological functions.
    Current opinion in immunology 10/2010; 22(6):698-705. DOI:10.1016/j.coi.2010.09.002 · 7.87 Impact Factor
Show more