Influence of family history of cardiovascular disease on clinicians' preventive recommendations and subsequent adherence of patients without cardiovascular disease.
ABSTRACT Family history of cardiovascular disease (CVD) is an independent risk factor for CVD. Therefore, efforts to prevent CVD among asymptomatic persons with a family history are warranted. Little is known about preventive recommendations clinicians offer their patients with a family history of CVD, and adherence to preventive recommendations by patients at risk for CVD has not been well described.
We used the 2007 Oregon Behavioral Risk Factor Surveillance System to evaluate among 2,566 adults without CVD associations between family history of CVD and (a) clinician recommendations; (b) perceived risk of developing CVD; (c) adoption of preventive and screening behaviors; and (d) risk factors of CVD.
Compared with adults with no family history of CVD, those with a family history reported that their clinician was more likely to ask about their family history information (OR = 2.6; 95% CI, 1.9-3.4), discuss the risk of developing CVD (OR = 2.0; 95% CI, 1.6-2.5), and make recommendations to prevent CVD (OR = 2.1; 95% CI, 1.7-2.7). Family history and clinician recommendations were associated with a higher likelihood of reported changes in diet or physical activity to prevent CVD (OR = 2.7; 95% CI, 2.3-3.2). Persons with a family history of CVD were more likely to report having high cholesterol, having high blood pressure, taking aspirin, and having had their cholesterol checked.
The presence of a family history of CVD appears to prompt clinicians to recommend preventive changes and may motivate patients without CVD to adopt these recommendations.
SourceAvailable from: Muin J Khoury[Show abstract] [Hide abstract]
ABSTRACT: State health departments in Michigan, Minnesota, Oregon, and Utah explored the use of genomic information, including family health history, in chronic disease prevention programs. To support these explorations, the Office of Public Health Genomics at the Centers for Disease Control and Prevention provided cooperative agreement funds from 2003 through 2008. The 4 states' chronic disease programs identified advocates, formed partnerships, and assessed public data; they integrated genomics into existing state plans for genetics and chronic disease prevention; they developed projects focused on prevention of asthma, cancer, cardiovascular disease, diabetes, and other chronic conditions; and they created educational curricula and materials for health workers, policymakers, and the public. Each state's program was different because of the need to adapt to existing culture, infrastructure, and resources, yet all were able to enhance their chronic disease prevention programs with the use of family health history, a low-tech "genomic tool." Additional states are drawing on the experience of these 4 states to develop their own approaches.Preventing chronic disease 06/2014; 11:E97. DOI:10.5888/pcd11.130267 · 1.96 Impact Factor
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ABSTRACT: Objective: Family history, one of the traditional tools in clinical medicine, is frequently neglected which can be used to identify persons at increased cardiovascular disease (CVD) risk. The present study aimed to determine the influence of family history on cardiovascular health. Methodology: A cross sectional study was conducted on the retired defense personnel to study the relation of socio-demographic varia-bles, physical activity, body mass index, sleep, stress and metabolic syndrome with family history from Jun to Oct, 2013. Chi Square test was used with statistical significance of P value <0.05. Results: A positive family history was reported among 32.77% of the study subjects with statistically significant higher recording by females (60.87%; P <0.01), those who were aged 20-60years (62.60%; P<0.001), and had higher education level (42.61%; P<0.05). A statistically significant stress (29.56%; P<0.001), sedentary lifestyle (72.17%; P<0.05) and insomnia (29.56%) was reported among sub-jects reporting positive family history. A statistically significant prevalence of metabolic syndrome (36.53%; P<0.05), hypertension (56.52%; P<0.01), obesity (54.78%), dyslipidemia (33.05%; P<0.05) and dysglycemia (31.31%; P<0.05) was more in subjects reporting positive than negative family history (metabolic syndrome: 23.73%; (P<0.05); hypertension: 41.52% (P<0.01); obesity: 50.00%; dyslipidemia: 21.61% (P<0.05); dysglycemia: 21.19% (P<0.05)). Conclusions: A statistical association between positive family history and metabolic syndrome shows CVD susceptibility which prompts to utilize every opportunity to involve concerned families in health education by promoting healthy lifestyle changes in their diet and physical activity. Keywords: Cardiovascular Disease, Family History, Metabolic Syndrome.
Article: Genomics in Primary Care Practice[Show abstract] [Hide abstract]
ABSTRACT: This article discusses the clinical utility of genomic information for personalized preventive care of a healthy adult. Family health history is currently the most applicable genomic predictor for common, multifactorial diseases, and can also show patterns that suggest an inherited high susceptibility to a particular form of cancer or other disease. Both bloodline ancestry and shared environmental factors are important predictors for many disease states. DNA and family history analyses give information that is probabilistic, not deterministic. Therefore, family history can highlight behavioral, social, or cultural risk factors that can be modified to prevent diseases.Primary care 06/2014; 41(2):421-435. DOI:10.1016/j.pop.2014.02.012 · 0.81 Impact Factor