Mammary fat necrosis following radiotherapy in the conservative management of localized breast cancer: does it matter?
ABSTRACT Fat necrosis is a well-described and relatively common complication arising from post-lumpectomy irradiation of the breast, most commonly breast brachytherapy. We wish to assess the clinical significance of fat necrosis resulting from post-lumpectomy breast irradiation.
We reviewed the literature to determine the overall incidence and significance of fat necrosis to determine whether or not fat necrosis poses a significant clinical problem.
Fat necrosis occurs in up to one-quarter of patients following post-lumpectomy breast irradiation. Only rarely is invasive intervention required however, it does significantly degrade the quality of all modalities of breast imaging.
Fat necrosis is a common complication of radiotherapy which rarely requires therapeutic intervention. However, post-therapeutic clinical imaging such as mammography, ultrasound and magnetic resonance imaging are affected which may result in additional diagnostic procedures up to and including biopsy.
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ABSTRACT: The most complicated step in decoding BCH codes is the algebraic operation of converting the syndrome vector derived from a received data vector into an error location polynomial over the finite field GF (2<sup>m</sup>). The classic method uses Berlekamp's iterative algorithm to fill rows of a table with various quantities including partial polynomials until a maximum row is reached. Where this occurs depends on the distance of the code. This process is tedious, time-consuming, and is difficult to realize in hardware. The complete closed solution to the algorithm for each t ⩽5 is presented as a set of decision trees. The only computation required is the numeric evaluation of one formula over GF (2<sup>m</sup>) at each level of the tree as well as the evaluation of a formula for each coefficient in the resulting polynomial. The closed solution is more easily realized in hardware or software than the iterative algorithm, and it is shown by simulation that the closed solution is considerably faster even though some of the formulas are rather long. Also, the closed formulas can be proven correct, where it is almost impossible to totally verify an implementation of the iterative methodCommunications, 1990. ICC '90, Including Supercomm Technical Sessions. SUPERCOMM/ICC '90. Conference Record., IEEE International Conference on; 05/1990
- Radiotherapy and Oncology 07/2011; 100(1):1-6. DOI:10.1016/j.radonc.2011.07.011
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ABSTRACT: Oncoplastic surgery has revolutionized the field of breast conserving surgery (BCS). The final aims of this technique are to obtain an adequate resection margin that will reduce the rate of local recurrence while simultaneously improving cosmetic outcomes. To obtain successful results after oncoplastic surgery, it is imperative that patients be risk-stratified based on risk factors associated with positive margins, that relevant imaging studies be reviewed, and that the confirmation of negative margins be confirmed during the initial operation. Patients who had small- to moderate-sized breasts are the most likely to be dissatisfied with the cosmetic outcome of surgery, even if the defect is small; therefore, oncoplastic surgery in this population is warranted. Reconstruction of the remaining breast tissue is divided into volume displacement and volume replacement techniques. The use of the various oncoplastic surgeries is based on tumor location and excised breast volume. If the excised volume is less than 100 g, the tumor location is used to determine which technique should be used, with the most commonly used technique being volume displacement. However, if the excised volume is greater than 100 g, the volume replacement method is generally used, and in cases where more than 150 g is excised, the latissimus dorsi myocutaneous flap may be used to obtain a pleasing cosmetic result. The local recurrence rate after oncoplastic surgery was lower than that of conventional BCS, as oncoplastic surgery reduced the rate of positive resection margins by resecting a wider section of glandular tissue. If the surgeon understands the advantages and disadvantages of oncoplastic surgery, and the multidisciplinary breast team is able to successfully collaborate, then the success rate of BCS with partial breast reconstruction can be increased while also yielding a cosmetically appealing outcome.12/2011; 14(4):253-61. DOI:10.4048/jbc.2011.14.4.253