Article

May Toxoplasma gondii increase suicide attempt-preliminary results in Turkish subjects?

Erciyes University, Medical Faculty, Department of Forensic Medicine, Turkey.
Forensic science international (Impact Factor: 2.12). 03/2010; 199(1-3):15-7. DOI: 10.1016/j.forsciint.2010.02.020
Source: PubMed

ABSTRACT Suicide attempts are one of the risk factors of suicide. Possible mechanisms by which Toxoplasma gondii may affect human behavior and it may also cause humans to attempt suicide. The aim of this study is to find out whether or not T. gondii is one of the reasons in suicide attempts. We investigated the sero-positivity level for anti-Toxoplasma IgG and IgM antibodies by enzyme-linked immunosorbent assay in subjects who have attempted to suicide to find out whether there is a probable relationship between T. gondii and suicide attempts. In our study, we selected 200 cases of suicide attempts and 200 healthy volunteers. The sero-positivity level for anti-Toxoplasma IgG antibodies among suicide attempts (41%) was significantly higher than the control group (28%). This signifies that there might be a causal relationship between toxoplasmosis and the etiology of suicide attempt.

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    • "Otherwise, associations between asthma and increased SI and suicide attempts were reported among adults in the community , and young people hospitalized for asthma (Goodwin and Eaton 2005; Goodwin et al. 2005). Strong evidence of an association between T. gondii and SB (Okusaga and Postolache 2012) was also unveiled in cross-sectional studies (Arling et al. 2009; Yagmur et al. 2010; Ling et al. 2011; Okusaga et al. 2011; Zhang et al. 2012). A prospective cohort study on 45 788 women showed a predictive association between T. gondii IgG antibody levels and selfdirected violence, violent suicide attempts, and suicide in later life (Pedersen et al. 2012). "
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