Evidence for the efficacy of complementary and alternative medicines in the management of fibromyalgia: a systematic review
ABSTRACT To critically evaluate the evidence regarding complementary and alternative medicines (CAMs) taken orally or applied topically for the treatment of FM.
Randomized controlled trials of FM using CAMs, in comparison with other treatments or placebo, published in English up to March 2009, were eligible for inclusion. They were identified using systematic searches of bibliographic databases and manual searching of reference lists. Information was extracted on outcomes, and statistical significance, in comparison with alternative treatment or placebo, and side effects were reported. The methodological quality of the primary studies was determined.
Single studies on four CAMs, and three on different approaches to homeopathic care were identified. Their methodological quality was moderate. The homeopathy studies were small, but each reported an improvement in pain. The effects of anthocyanidins, capsaicin and S-adenosylmethionine each showed at least one statistically significant improved outcome compared with placebo. However, the studies of anthocyanidins and capsaicin only demonstrated an improvement in a single outcome, sleep disturbance and tenderness, respectively, of several outcomes considered. No evidence of efficacy was found regarding Soy in a single study. Most of these CAMs were free of major adverse effects and usually associated with only minor adverse effects such as dizziness, nausea and stomach upsets.
There is insufficient evidence on any CAM, taken orally or applied topically, for FM. The small number of positive studies lack replication. Further high-quality trials are necessary to determine whether these initial findings can be supported by a larger evidence base.
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ABSTRACT: The purpose of this study was to identify the correlations between disease related factors and disturbance of daily living in patients with fibromyalgia. A descriptive survey study design was used. Data were collected from 45 out patients diagnosed of fibromyalgia according to the conditions by American College of Rheumatology in I-city. The mean score of tender points were 15.00, fatigue was 8.67, quality of sleep was 12.94 and depression was 23.70. They have struggled with fibromyalgia for 6 years on an average. Among patients, 42.2% had to discontinue their job/learning due to their disease, and experienced a disturbance of daily living for 41.79 days during last 3 months. There were significant positive correlations between disturbance of daily living and tender points, depression, between fatigue and depression, quality of sleep, between quality of sleep and depression. As a result, fibromyalgia patients suffered from various disease related factors and disturbance of daily living. Therefore, it can be suggested that the consideration of these related factors is important to develope intervention program for the better qualified life of the patients.07/2011; 11(7). DOI:10.5392/JKCA.2011.11.7.239
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ABSTRACT: Fibromyalgia is a syndrome characterized by chronic widespread pain, stiffness, nonrestorative sleep, fatigue, and comorbid conditions. Recognition of the condition and its associated medications and challenges, along with knowledge of treatment modifications and precautions in drug prescription, can ensure safe and effective delivery of oral health care in fibromyalgia patients. The ever-evolving research into the condition makes it necessary for the oral health care provider to be informed about the current state of the literature and treatment standards regarding the management of fibromyalgia patients. This article reviews the epidemiology, etiology, pathophysiology, and clinical presentation of fibromyalgia, as well as therapeutic advances. Also highlighted are issues that are important to the oral health care provider, including orofacial manifestations and oral health care considerations for patients with fibromyalgia.01/2014; 28(2):107-18.
Dataset: FIBROMYALGIA PUBLISHED ARTICLE