Propionibacteria used as probiotics - A review
ABSTRACT The investigation of probiotics has been very intensive during the last decades, con-centrating mainly on lactic acid and bifidobacteria. But there is also clear evidence that propionibacteria have probiotic effects. The probiotic influence is based on the production of propionic acid, bacteriocins, vitamin B12, better exploitation of fodder, growth stimulation of other beneficial bacteria and the ability to stay alive during gastric digestion. In Finland, large test series with piglets receiving Propionibacterium freudenreichii in their fodder have been performed. The growth promotant effect was significant and the fodder demand was clearly lower when compared with the control group. The bacterial concentration used was, on average, 2x109 cfu / g and the dose / animal 1-5 g / d. The mineral and trace element contents of a Propionibacterium freudenreichii-mass have also been studied. In other European countries, mixtures of propionibacteria and lactic acid / bifidobacteria have been used with positive results as probiotics for calves, Propionibacteria have also been investigated as human probiotics, especially in curing intestinal disorders of children and elderly people. The occurrence of lactic acid bacteria and propionibacteria in living food is very interesting as different kinds of this food type obviously act as probiotics. Thus, propionibacteria can be considered as potential probiotics requiring further research. Durant les dernières décennies, la recherche de probiotiques a été très intense, principalement sur les bactéries lactiques et les bifidobactéries. Mais il est également évident que les bactéries propioniques ont des effets probiotiques. Leur activité probiotique est basée sur la production d'acide propionique, de bactériocines, de vitamine B12, la meilleure utilisation des fourrages, la stimulation de la croissance des autres bactéries bénéfiques et la capacité à survivre au cours de la digestion gastrique. En Finlande, un test à grande échelle a été effectué sur des porcelets auxquels on incorporait Propionibacterium freudenreichii à la nourriture. L'effet sur la promotion de la croissance était significatif et la demande de fourrage était nettement plus basse comparée au groupe contrôle. La concentration bactérienne utilisée était en moyenne de 2 x 109 ufc / g et la dose par animal de 1-5 g / jour. Les teneurs en minéraux et oligoéléments d'une biomasse de Propionibacterium freudenreichii ont également été étudiées. Dans d'autres pays européens, des mélanges de bactéries propioniques et lactiques / bifidobactéries ont été utilisés comme probiotiques pour les veaux, avec des résultats positifs. Les bactéries propioniques ont aussi été utilisées et examinées comme probiotiques chez l'homme, spécialement pour soigner les désordres intestinaux des enfants et des personnes âgées. La présence de bactéries lactiques et de bactéries propioniques dans les aliments vivants est très intéressante puisque plusieurs sortes d'aliments de ce type agissent manifestement comme probiotiques. Les bactéries propioniques peuvent donc être considérées comme des probiotiques potentiels nécessitant de plus amples recherches.
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ABSTRACT: Aims: The current study aimed at assessing, in vitro, the potential use of probiotics for the skin.Methods and Results: Propionibacteria were chosen as potential probiotics as they are members of the normal cutaneous microbiota. Dairy strains were chosen because of their documented safe use. Production of anti-microbial substances was assessed, against selected skin pathogens. Only production of organic acids was detected. Two of the tested strains were found to exhibit high adhesion to human keratin, in vitro. Despite this high adhesion, no inhibition of skin pathogen adhesion to human keratin was observed.Conclusions: The current strains assessed may not be optimal for use as skin probiotics. However, the results of the study show that the methodology works for investigating this kind of application.Significance and Impact of the Study: Methods for selecting probiotics for potential application on the skin are presented.Letters in Applied Microbiology 04/2003; 36(5):327 - 331. · 1.63 Impact Factor
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ABSTRACT: Propionic acid bacteria (PAB) possess a set of physiological and biochemical properties that allows their inclusion in probiotic compositions. Their potential resources are underestimated as yet. The list of the described probiotic characteristics of PAB must be enlarged by the addition of antimutagenic, reactivative and protective activities, first discovered by our group. Live and dead cells of PAB and Luteococcus casei as well as their cultural liquid (CL) revealed antimutagenic (AM) effect on spontaneous and induced mutagenesis. Protective and reactivative activities of Propionibacterium freudenreichii cells are bound up with the intracellular protein, identified as cystein synthase, whose synthesis is induced by some stress factors. Under unfavourable conditions leading to lysis of the majority of cells, the released protein may play a vitally important role in the cell population as a whole, supporting the existence of the species. The active protein reveals cross-reactive properties, both the protective and reactivative effects on cells of Escherichia coli and yeasts Saccharomyces cerevisiae and Candida guilliermondii. Phylogenetically close to PAB, L. casei produces and excretes in the medium a proteinaceous metabolite, possessing protective and reactivative effects on cells of the producer, E. coli, S. cerevisiae and C. scottii, treated by heating and UV irradiation. The exometabolite is synthezed by cells in the log phase of growth. The effectiveness of its impact inversely depends on the survival of microbes. CL of L. casei is considered as the source of a new prebiotic with reactivative and protective properties.07/2009; 20(2):109-112.
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ABSTRACT: Nowadays, there is an increasing concern for the public health about the consequences from the long and increased use of antibiotics in livestock production. The use of antibiotics in animal feed as growth promoters has been completely banned by the European Union since 2006, based on their possible negative effects on human and animal health. The removal of growth promoters has led to animal performance problems and a rise in the incidence of certain animal diseases. Thus, there is an urgent need to find alternatives to antibiotics, especially in EU. Due to the modern consumers’ concern about the potential development of antibiotic-resistant bacteria as well as at the same time the need to prevent economic losses of the farmers, alternatives to antibiotics has been developed to prevent the health problems and to improve the growth performance in farm animals. Owing to the full ban of antibiotic use in EU there is an urgent need to find alternatives to in-feed antibiotics. New strategies and commercial products must be developed to improve animal health and performance, based on their safety, efficacy and cost-effectiveness. The aim of this study is to summarize the beneficial effects of currently used alternatives to in-feed antibiotics, i.e. probiotics, prebiotics, organic acids, phytogenic compounds and zeolites on health and growth performance in farm animals (swine, poultry and ruminants).CAB Reviews Perspectives in Agriculture Veterinary Science Nutrition and Natural Resources 04/2013; 8(32).