Article

Dementia Incidence Continues to Increase with Age in the Oldest Old The 90+Study

Department of Neurology, University of California, Irvine, CA 92697-1400, USA.
Annals of Neurology (Impact Factor: 11.91). 01/2010; 67(1):114-21. DOI: 10.1002/ana.21915
Source: PubMed

ABSTRACT The oldest old are the fastest growing segment of the US population, and accurate estimates of dementia incidence in this group are crucial for healthcare planning. Although dementia incidence doubles every 5 years from ages 65 to 90 years, it is unknown if this exponential increase continues past age 90 years. Here, we estimate age- and sex-specific incidence rates of all-cause dementia in people aged 90 years and older, including estimates for centenarians.
Participants are from The 90+ Study, a population-based longitudinal study of aging and dementia. Three hundred thirty nondemented participants aged 90 years and older at baseline were followed between January 2003 and December 2007. Age- and sex-specific incidence rates of all-cause dementia were estimated by person-years analysis.
The overall incidence rate of all-cause dementia was 18.2% (95% confidence interval [CI], 15.3-21.5) per year and was similar for men and women (risk ratio, 0.94; 95% CI, 0.65-1.37). Rates increased exponentially with age from 12.7% per year in the 90-94-year age group, to 21.2% per year in the 95-99-year age group, to 40.7% per year in the 100+-year age group. The doubling time based on a Poisson regression was 5.5 years.
Incidence of all-cause dementia is very high in people aged 90 years and older and continues to increase exponentially with age in both men and women. Projections of the number of people with dementia should incorporate this continuing increase of dementia incidence after age 90 years. Our results foretell the growing public health burden of dementia in an increasingly aging population.

0 Followers
 · 
157 Views
  • Source
    e-book Promoting conscious and active learning and aging; 01/2013
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Background: Despite the increasing older population providing care for family members with dementia at home, there is no consensus in the literature in terms of how caring impacts on their quality of life (QoL) and the association of the family carer’s age with QoL outcomes. Aims: To explore the available literature investigating the QoL of older family carers (family carers aged ≥ 60) and the association of family carers’ age and QoL outcomes in a dementia context. Methods: A review of the literature to December 2013 was conducted using Embase-OVID, CINAL, Medline-OVID, Psyc INFO-OVID, Grey literature and the references of the included studies. Cross-sectional or prospective longitudinal studies published in English were eligible. The selection and appraisal processes were performed by two reviewers independently and the methodological quality was assessed by STROBE statement. Results: From the 12 selected studies, 4 were carried out with older family carers’ samples and 8 associated the variable ‘age’ with QoL outcomes. Eight different instruments were used to assess family carers’ QoL, however none were designed specifically for older people or older family carers. The mean age of the carers’ samples ranged from 55.2 to 76.0 years old. Older family carers showed low levels of QoL and were often below the age-matched standard population. Carers’ age was negatively correlated with QoL outcomes in most of the studies. Conclusion: Older people are increasingly involved with dementia care and family carer’s advanced age was shown to be associated with low levels of QoL. Future research should investigate the QoL of older family carers separately and use QoL instruments containing older family carers’ specific needs and perspectives of QoL. In planning care and support, primaryhealth care practitioners should consider family carer’s age group and their specific needs
    Quality in primary care 03/2015; 23(1):18-30.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Aging of population is currently a global phenomenon. At least one in 5 people over the age of 65 years will suffer from a mental disorder by 2030. Study of psychiatric morbidities in this age group is essential to prepare for upcoming challenges. To find out the prevalence of different psychiatric morbidities in elderly population and to find out if there are any age and gender specific differences. Retrospective review; Psychiatric outpatient department of Manipal Teaching Hospital, Pokhara, Nepal. Data for patients ≥ 65 years of age attending the psychiatric outpatient department of Manipal Teaching Hospital, Pokhara, Nepal, from 1(st) January 2012 to 15(th) January 2013 were collected retrospectively in a predesigned proforma. Risk of having different psychiatric disorders was estimated using odds ratio. The mean age of 120 patients included in this study was 69.67 (SD = 5.94) years. Depressive disorder (26.7%) was the most common diagnosis. There was no statistically significant difference in psychiatric disorders in >75 years compared with ≤75 years except for dementia [odd ratio (OR) (≤75 years/>75 years)=0.055, 95% confidence interval (CI)=0.016; 0.194]. Alcohol dependence syndrome [OR (male/female)=7.826, 95% CI = 1.699;36.705] and dementia [OR (male/female)=3.394, 95% CI = 1.015;11.350] was more common in males. Depressive disorder was the most common psychiatric morbidity among the elderly patients. The odds suffering from dementia increased with increasing age. The odds of having alcohol related problems and dementia were more in males compared with females.
    Industrial psychiatry journal 07/2014; 23(2):101. DOI:10.4103/0972-6748.151673

Full-text (2 Sources)

Download
25 Downloads
Available from
Jul 3, 2014